stem cells are self-renewing and undifferentiated cell types that can be differentiate into functional cells. stem cells can be classified into two main types based on their source of origin: embryonic and adult stem cells. stem cells also classified based on the range of differentiation potentials into totipotent, pluripotent, multipotent, and unipotent. multipotent stem cells have the ability...

Fertility preservation has gained increased acceptance, and many reproductive medicine centers have established programs for this service. A recent report, which collected data from all Nordic university hospitals that had initiated programs for fertility preservation (N = 14), found that breast cancer is the most common diagnosis among women who underwent procedures aimed at fertility preserva...

Background Increasing survival rates in patients who suffer from oncological disease and improvement in reproductive medicine techniques has led to increasing use of different fertility preservation methods. The evidence supporting current and forthcoming options for fertility preservation consisted of two main parts as for female and male. Fertility preservation options for female and male dep...

Chemotherapy has the potential to deplete and destroy a woman's reproductive potential. Although many oncologists are referring women for fertility preservation before chemotherapy, in many cases there is limited time for fertility preservation. This review provides an overview of the impact of cancer and chemotherapy on the ovarian reserve, a summary of methods of fertility preservation prior ...

Fertility preservation procedures are indicated when it's predicted that there will be exposure to a cause of infertility. Mainly cancer treatment, such as chemotherapy, radiation, and surgery, may destroy a person's ability to have children later in life, and oncofertility research focuses on increasing fertility preservation options. Oncofertility is a subfield that bridges oncology and repro...

Fertility preservation procedures are indicated when it's predicted that there will be exposure to a cause of infertility. Mainly cancer treatment, such as chemotherapy, radiation, and surgery, may destroy a person's ability to have children later in life, and oncofertility research focuses on increasing fertility preservation options. Oncofertility is a subfield that bridges oncology and repro...

Gynecologic malignancies account for 1.09 million new cancer cases worldwide and for about 12% of the tumors affecting females. Approximately 10% of all female cancer survivors are aged 40 years or younger. Since cancers affecting female genital organs are usually treated with radical surgery, chemotherapy or chemoradiotherapy – approaches that induce permanent reproductive function impairment ...

Fertility preservation in the young cancer survivor is recognized as a key survivorship issue by the American Society of Clinical Oncology and the American Society of Reproductive Medicine. Thus, health-care providers should inform women about the effects of cancer therapy on fertility and should discuss the different fertility preservation options available. It is also recommended to refer wom...

As the number of cancer survivors continues to increase, oncologists are faced with the challenge of providing cancer therapy to patients who may 1 day want to have children. Yet, gonadotoxic cancer treatments can compromise future fertility, either temporarily or permanently. There are established means of preserving fertility before cancer treatment; specifically, sperm cryopreservation for m...

Fertility preservation is feasible in the majority of men. Herein, we review the reproductive toxicities of commonly encountered clinical threats to male fertility, including cancer, radiotherapy, chemotherapy, surgery, and nonmalignant diseases treated with immunosuppression. Other scenarios, in which fertility preservation may be considered, such as Klinefelter syndrome, acute testicular inju...