The effect on cholesterol synthesis of ligation of the common bile duct was studied in the rat. The bile ducts of rats were ligated; 24 to 48 hours later, estimates of the rate of cholesterol synthesis were made, either by injection of labelled water or acetate into the intact animal, or by incubation of slices or homogenates of the liver in the presence of 1-C(14)-acetate. These various criter...

This study was aimed at finding the effect of palm oil diets on the small intestinal motor activity and transit in rats. Adult albino Wistar rats were divided into three groups of ten rats each. The first group was fed on rat chow containing 15% (wt/wt) of fresh palm oil diets for fifteen weeks. The second was fed on rat chow containing 15% (wt/wt) thermally oxidized diet while the third group ...

background and aim: omega 3 of essential fatty acids, especially in fish oil form plays an important role in structural, functional, and biological aspects in body. omega 3 deficiency can have devastating effects on the nervous system and auditory. this study aimed to evaluate auditory threshold in n-3 fatty acid-deficient rat pups following supplementation of fish oil consumption during the suc...

objective: walnut (juglans regia) is a domestic fruit of iran. walnut kernel (wk) has many beneficial constituents such as unsaturated fatty acids, antioxidants, and vitamin e. scientific studies have shown that fatty acids and vitamin e can modulate learning and memory processes. the aim of the present work was to study effects of walnut consumption by mothers during pregnancy and lactation on...

The purpose of this study was to investigate the potential role of creatine in GLUT4 gene expression in rat skeletal muscle. Female Wistar rats were fed normal rat chow (controls) or chow containing 2% creatine monohydrate ad libitum for 3 wk. GLUT4 protein levels of creatine-fed rats were significantly increased in extensor digitorum longus (EDL), triceps, and epitrochlearis muscles compared w...

A cDNA encoding an Na+-Pi co-transporter, termed rat PiT-1, has now been isolated from rat parathyroid. Expression of rat PiT-1 in Xenopus oocytes revealed that it possesses Na+-dependent Pi co-transport activity. The amount of PiT-1 mRNA in the parathyroid of vitamin D-deficient rats was reduced compared with that in normal animals, and increased markedly after administration of 1,25-dihydroxy...

The effect of ascorbic acid deficiency on serum levels of high density lipoprotein- (HDL-), low density lipoprotein- (LDL-), very low density lipoprotein- (VLDL-) and chylomicron-cholesterol was examined in ODS-od/od rat (ODS rat), that is a rat mutant unable to synthesize ascorbic acid. Male ODS rats were fed an ascrobic acid-free diet for 20 days. In another two groups, the diet supplemented ...

Production, recycling, and elimination of urea are important to maintain nitrogen balance. Adaptation to varying loads of urea due to different protein intake or in renal failure may involve changes in urea transport and may possibly affect urea transporters. In this study, we examined the expression of the UT-B urea transporter in rats fed a low-protein diet (LPD), a high-protein diet (HPD), a...

L-carnitine is essential for energy production and fatty acid metabolism. This study was designed to evaluate effects of L-carnitine on liver enzymes in rats fed cholesterol rich diet. Thirty two healthy male Wistar Albino rats were divided to four groups as Control (K), Cholesterol (C), L-carnitine (L) and L-carnitine+cholesterol (LC). All rats were kept in individual cages during the experime...