نتایج جستجو برای: fecal microbiota

تعداد نتایج: 52550  

2012
Ian M. Carroll Tamar Ringel-Kulka Jennica P. Siddle Todd R. Klaenhammer Yehuda Ringel

The handling and treatment of biological samples is critical when characterizing the composition of the intestinal microbiota between different ecological niches or diseases. Specifically, exposure of fecal samples to room temperature or long term storage in deep freezing conditions may alter the composition of the microbiota. Thus, we stored fecal samples at room temperature and monitored the ...

2015
Alexa Weingarden Antonio González Yoshiki Vázquez-Baeza Sophie Weiss Gregory Humphry Donna Berg-Lyons Dan Knights Tatsuya Unno Aleh Bobr Johnthomas Kang Alexander Khoruts Rob Knight Michael J Sadowsky

BACKGROUND Fecal microbiota transplantation (FMT) is an effective treatment for recurrent Clostridium difficile infection (CDI) that often fails standard antibiotic therapy. Despite its widespread recent use, however, little is known about the stability of the fecal microbiota following FMT. RESULTS Here we report on short- and long-term changes and provide kinetic visualization of fecal micr...

Journal: :Statistical methods in medical research 2017
Scott W Olesen Thomas Gurry Eric J Alm

Fecal microbiota transplantation is a highly effective intervention for patients suffering from recurrent Clostridium difficile, a common hospital-acquired infection. Fecal microbiota transplantation's success as a therapy for C. difficile has inspired interest in performing clinical trials that experiment with fecal microbiota transplantation as a therapy for other conditions like inflammatory...

Ahmadi, Yazdan, Shabanzadeh, Parisa,

Background: Over the past half-century, the prevalence of obesity and related metabolic disorders such as fat disorders, cardiovascular disease, myocardial infarction and stroke have increased dramatically. Various types of organisms, including bacteria, fungi, protozoan, and viruses, have evolved to live in the human gut, called microbiota. Scientists have found that thin people have a balance...

2017
Nadia Gaci Prem Prashant Chaudhary William Tottey Monique Alric Jean-François Brugère

Background: The availability of fresh stool samples is a prerequisite in most gut microbiota functional studies. Objective: Strategies for amplification and long-term gut microbiota preservation from fecal samples would favor sample sharing, help comparisons and reproducibility over time and between laboratories, and improve the safety and ethical issues surrounding fecal microbiota transplanta...

2017
Michelle M O' Donnell Hugh M B Harris R Paul Ross Paul W O'Toole

In this pilot study, we determined the core fecal microbiota composition and overall microbiota diversity of domesticated herbivorous animals of three digestion types: hindgut fermenters, ruminants, and monogastrics. The 42 animals representing 10 animal species were housed on a single farm in Ireland and all the large herbivores consumed similar feed, harmonizing two of the environmental facto...

2016
MIHAELA LASZLO LIDIA CIOBANU VASILE ANDREICA OLIVIU PASCU

BACKGROUND AND AIMS Fecal microbiota transplantation is used with success in persistent (more than two episodes) Clostridium Difficile Infection; it has also gained importance and started to be used in inflammatory bowel disease. There are theoretical arguments that justify its use in ulcerative colitis or Crohn's disease. Based on our clinical cases we tried to evaluate the indications of feca...

2017
Xiaodong Yang Yiwei Qian Shaoqing Xu Yanyan Song Qin Xiao

Recent studies reported an association between gut microbiota composition and Parkinson's disease (PD). However, we know little about the relationship between microbiome dysbiosis and the pathogenesis of PD. The objective of this study was to describe the evolution of fecal microbiota using an oral rotenone model of PD from a longitudinal study over a period of 4 weeks. Gastrointestinal functio...

2015
Arancha Hevia Susana Delgado Abelardo Margolles Borja Sánchez

The idea of considering the gut microbiota as a virtual human organ has led to the concept of fecal microbiota transplantation (FMT), which has recently been extremely successful in the treatment of cases of recurrent Clostridium difficile infection. Administration of safe, viable, and representative fecal microbiota is crucial for FMT. To our knowledge, suitable techniques and systematic condi...

Journal: :Science 2013
Vanessa K Ridaura Jeremiah J Faith Federico E Rey Jiye Cheng Alexis E Duncan Andrew L Kau Nicholas W Griffin Vincent Lombard Bernard Henrissat James R Bain Michael J Muehlbauer Olga Ilkayeva Clay F Semenkovich Katsuhiko Funai David K Hayashi Barbara J Lyle Margaret C Martini Luke K Ursell Jose C Clemente William Van Treuren William A Walters Rob Knight Christopher B Newgard Andrew C Heath Jeffrey I Gordon

The role of specific gut microbes in shaping body composition remains unclear. We transplanted fecal microbiota from adult female twin pairs discordant for obesity into germ-free mice fed low-fat mouse chow, as well as diets representing different levels of saturated fat and fruit and vegetable consumption typical of the U.S. diet. Increased total body and fat mass, as well as obesity-associate...

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