drug utilization evaluation (due) studies facilitate assessing the appropriateness and rational use of medications.the goal of the present study was to evaluate amphotericin b usage in neutropenic patients. a prospective due study was performed in hematology-oncology and stem cell transplantation wards at taleghani hospital for one-year. national comprehensive cancer network, clinical practice ...

Chemotherapy-induced neutropenia is a common complication in cancer treatment. In this study, we investigated chemotherapy-induced neutropenia that was recently detected in all patients with gynecologic malignancy. Between January 2009 and December 2011, we examined cases of chemotherapy-induced neutropenia reported in our hospital. We analyzed the incidence and clinical features of chemotherap...

INTRODUCTION Febrile neutropenia is a common complication of chemotherapy treatment of malignant hematological diseases. However, there is insufficient information regarding the infectious complications of febrile neutropenia in our country. Objective. We will evaluate the microbial characteristics of bacterial and fungal isolates and the clinical outcome of patients with febrile neutropenia wh...

Febrile neutropenia is one of the most serious complications in patients with haematological malignancies and chemotherapy. A prompt identification of infection and empirical antibiotic therapy can prolong survival. This paper reviews the guidelines about febrile neutropenia in the setting of hematologic malignancies, providing an overview of the definition of fever and neutropenia, and categor...

PURPOSE/OBJECTIVES To determine the time frame for evaluation and treatment of adult patients with febrile neutropenia in the emergency department (ED). DESIGN Prospective, descriptive survey. SETTING ED in a large, urban, academic health center. SAMPLE 19 patients with febrile neutropenia during 23 ED visits in eight months. METHODS Demographic and treatment variables and durations of ...

This article evaluates the feasibility of developing and implementing a computer-based risk assessment tool (CBRAT) for febrile neutropenia and determines whether it could improve documentation of risk assessment in patients starting myelosuppressive chemotherapy regimens. The CBRAT was designed using a template creator in a commercial electronic medical records system. The effectiveness of the...

BACKGROUND Chemotherapy with platinum agent and etoposide for small-cell lung cancer (SCLC) is supposed to be associated with intermediate risk (10-20%) of febrile neutropenia. Primary prophylaxis with granulocyte colony-stimulating factors (G-CSFs) is not routinely recommended by the treatment guidelines. However, in clinical practice febrile neutropenia is often observed with standard etoposi...

background:  infections  in  neutropenic  patients  are  considered  as  major  causes  of  mortality and the emergence of drug resistance. gram positive bacterial infections are crucially important to be covered if indicated. vancomycin is active against most gram positive bacteria including methicillin resistant staphylococcus aureus (mrsa). in this study, we evaluated the appropriate utiliza...