OBJECTIVE Cellular microparticles (MP) are promising biomarkers in many pathological situations. Although flow cytometry (FCM) is widely used for their measurement, it has raised controversies because the smallest MP size falls below the detection limit of standard FCM (sd-FCM). Following recent technological improvements leading to high sensitivity FCM (hs-FCM), our objectives were (1) to eval...

This paper presents a hybrid differential evolution, particle swarm optimization and fuzzy c-means clustering algorithm called DEPSO-FCM for image segmentation. By the use of the differential evolution (DE) algorithm and particle swarm optimization to solve the FCM image segmentation influenced by the initial cluster centers and easily into a local optimum. Empirical results show that the propo...

The triple-frequency linear combination method can provide combinations with different characteristics and is one of the important methods to improve performance navigation services. Due large number performances, combinatorial clustering optimization very important, efficiency manual screening low. Firstly, based on basic model, objective equations are derived. Secondly, fuzzy c-means (FCM) al...

This study aims to empirically analyze teaching-learning-based optimization (TLBO) and machine learning algorithms using k-means fuzzy c-means (FCM) for their individual performance evaluation in terms of clustering classification. In the first phase, (k-means FCM) were employed independently accuracy was evaluated different computational measures. During second non-clustered data obtained from...

BACKGROUND The clinical usefulness of flow cytometry (FCM) for the diagnosis of leptomeningeal diseases (LMD) in non-Hodgkin lymphomas has been suggested in previous studies but needs to be further validated. With this regards, we evaluated the use of FCM for LMD in a series of Korean patients with non-Hodgkin lymphoma. METHODS FCM and cytomorphology were conducted using samples obtained from...

Several intravenous iron complexes are available for the treatment of iron deficiency anemia (IDA). Iron dextran (DEX) is associated with an elevated risk of potentially serious anaphylactic reactions, whereas others must be administered in several small infusions to avoid labile iron reactions. Ferric carboxymaltose (FCM) is a nondextran intravenous iron which can be administered in high singl...

The popular fuzzy c-means algorithm (FCM) converges to a local minimum of the objective function. Hence, different initializations may lead to different results. The important issue is how to avoid getting a bad local minimum value to improve the cluster accuracy. The particle swarm optimization (PSO) is a popular and robust strategy for optimization problems. But the main difficulty in applyin...

Ferric carboxymaltose (FCM, Ferinject) was effective and well tolerated in the treatment of iron-deficiency anemia (IDA) in nine, Phase III, randomized, controlled, multicenter trials in a diverse range of indications, including patients with inflammatory bowel disease (IBD), post-partum anemia (PPA) or abnormal uterine bleeding (AUB), chronic heart failure (CHF), non-dialysis-dependent chronic...

In this paper, we introduce a decomposition theory for fuzzy cognitive maps (FCMs). First, we partition the set of vertices of an FCM into blocks according to an equivalence relation, and by regarding these blocks as vertices we construct a quotient FCM. Second, each block induces a natural sectional FCM of the original FCM, which inherits the topological structure as well as the inference from...

1 Curso de Pós-Graduação em Saúde da Criança e do Adolescente, Faculdade de Ciências Médicas, Universidade Estadual de Campinas (FCM/ Unicamp), Campinas, SP, Brasil 2 Grupo Interdisciplinar de Estudos da Determinação e Diferenciação do Sexo (GIEDDS), FCM/ Unicamp, Campinas, SP, Brasil 3 Departamento de Pediatria, FCM/ Unicamp, Campinas, SP, Brasil 4 Departamento de Genética Médica, FCM/Unicamp,...