نتایج جستجو برای: fcεriα

تعداد نتایج: 54  

Journal: :Journal of nutritional science and vitaminology 2012
Koji Karasawa Hajime Otani

The effects of oral ingestion of a hot water extract of matured fruit of the date palm tree (Phoenix dactylifera L.) on allergic responses were investigated in mite-sensitized mice. Sneezing and nose rubbing events in mice given a date extract-added diet were significantly lower than in those given an extract-free (control) diet. The serum total and mite antigen-specific immunoglobulin (Ig) E l...

Journal: :American Journal of Respiratory Cell and Molecular Biology 2017

Journal: :Brain, Behavior, and Immunity 2017
Fan Liu Lubin Xu Naze Chen Mo Zhou Chunyan Li Qian Yang Yikuan Xie Yuguang Huang Chao Ma

Pruritus is the major symptom of ocular allergy but currently available treatments are often ineffective. Previous studies demonstrated that subpopulations of primary sensory neurons express Fc receptors and may contribute to antigen-specific pain. We investigated the role of neuronal Fc-epsilon Receptor I (FcεRI) in allergic ocular pruritus. Ovalbumin (OVA) was used as allergen together with a...

Journal: :Journal of immunology 2015
Susumu Yamazaki Nobuhiro Nakano Asuka Honjo Mutsuko Hara Keiko Maeda Chiharu Nishiyama Jiro Kitaura Yoshikazu Ohtsuka Ko Okumura Hideoki Ogawa Toshiaki Shimizu

FcεRI, which is composed of α, β, and γ subunits, plays an important role in IgE-mediated allergic responses. TGF-β1 has been reported to suppress FcεRI and stem cell factor receptor c-Kit expression on mast cell surfaces and to suppress mast cell activation induced by cross-linking of FcεRI. However, the molecular mechanism by which these expressions and activation are suppressed by TGF-β1 rem...

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