this paper presents the fatigue life behavior of hub using random vibration based on road roughness. the main objectives of this study are to predict the fatigue life and to identify the critical location for evaluating fatigue damage. asphalt road surface profiles obtained in favorable circumstances by topography cameras and in according road classification iso 2631-1estimate road roughness su...

Different cyclic loading modes have been used in in vitro fatigue studies of PMMA bone cement. It is unclear which loading mode is most appropriate from the perspective of the in vivo loading experienced by the cement in a cemented arthroplasty. Also, in different in vitro fatigue studies, different test specimen configurations have been used. The present work considers the influence of test sp...

This paper focuses on the finite element based fatigue life prediction of lower suspension arm, subjected to variable amplitude loading. The objectives of this study are to predict fatigue life of the lower suspension arm using stress-life and strain-life methods, to investigate the effect of the mean stress. The lower suspension arm was developed using computer aided design software. The finit...

BACKGROUND Calcitonin gene related peptide (CGRP) is a neuropeptide that is abundant in the sensory neurons which innervate bone. The effects of CGRP on isolated bone cells have been widely studied, and CGRP is currently considered to be an osteoanabolic peptide that has effects on both osteoclasts and osteoblasts. However, relatively little is known about the physiological role of CGRP in-vivo...

On rocky shores, wave-swept macroalgae experience dramatic and repeated wave-induced hydrodynamic forces. However, previous studies of macroalgal mechanics have shown that individual waves are not forceful enough to account for observed rates of breakage. Instead, fatigue may contribute to algal breakage, with damage accumulating over time in conditions of repeated loading. Here I examine the e...

Medical devices, particularly endovascular stents, manufactured from superelastic Nitinol, a near-equiatomic alloy of Ni and Ti, are subjected to complex mixed-mode loading conditions in vivo, including axial tension and compression, radial compression, pulsatile, bending and torsion. Fatigue lifetime prediction methodologies for Nitinol, however, are invariably based on uniaxial loading and th...

Medical devices, particularly endovascular stents, manufactured from superelastic Nitinol, a nearequiatomic alloy of Ni and Ti, are subjected to complex mixed-mode loading conditions in vivo, including axial tension and compression, radial compression, pulsatile, bending and torsion. Fatigue lifetime prediction methodologies for Nitinol, however, are invariably based on uniaxial loading and thu...

The complex structure of tendons relates to their mechanical properties. Previous research has associated the waviness of collagen fibers (crimp) during quasi-static tensile loading to tensile mechanical properties, but less is known about the role of fatigue loading on crimp properties. In this study (IACUC approved), mouse patellar tendons were fatigue loaded while an integrated plane polaris...

An important concept in bone mechanics is that osteons influence mechanical properties in several ways, including contributing to toughness and fatigue strength by debonding from the interstitial matrix so as to "bridge" developing cracks. Observations of "pulled out" osteons on fracture surfaces are thought to be indicative of such behavior. We tested the hypothesis that osteon pullout varies ...

16 This paper presents a novel large-area strain sensing technology for monitoring fatigue cracks in 17 steel bridges. The technology is based on a soft elastomeric capacitor (SEC), which serves as a 18 flexible and large-area strain gauge. Previous experiments have verified the SEC’s capability to 19 monitor low-cycle fatigue cracks experiencing large plastic deformation and large crack openin...