We have shown by machine proof that F24 = 22 24+1 is composite. The rigorous Pépin primality test was performed using independently developed programs running simultaneously on two different, physically separated processors. Each program employed a floating-point, FFT-based discrete weighted transform (DWT) to effect multiplication modulo F24. The final, respective Pépin residues obtained by th...

Despite being implicated as important intermediates, iron(V) compounds have proven very challenging to isolate and characterize. Here, we report the preparation of the iron(V) nitrido complex, [PhB((t)BuIm)(3)Fe(V)≡N]BAr(F24) (PhB((t)BuIm)(3)(-) = phenyltris(3-tert-butylimidazol-2-ylidene)borato, BAr(F24) = B(3,5-(CF(3))(2)C(6)H(3))(4)(-)), by one electron oxidation of the iron(IV) nitrido prec...

High-fructose diet is known to produce cardiovascular and metabolic pathologies. The objective was to determine whether the timing of high fructose (10% liquid solution) intake affect the metabolic and cardiovascular outcomes. Male C57BL mice with radiotelemetric probes were divided into four groups: (1) 24 h water (control); (2) 24 h fructose (F24); (3) 12 h fructose during the light phase (F1...

A multi-dimensional concatenation scheme for block codes is introduced, in which information symbols are interleaved and re-encoded for more than once. It provides a convenient platform to design high performance codes with flexible interleaver size. Coset based MAP soft-in/soft-out decoding algorithms are presented for the F24 code. Simulation results show that the proposed coding scheme can a...

Gunsalus and Sherman (1943) have shown that oxygen is necessary for glycerol fermentation for the majority of the lactic acid bacteria. These organisms, though considered devoid of those iron enzymes usually necessary when oxygen is involved as a hydrogen acceptor, could aerobically utilize glycerol. Because of the anomaly of these observations Gunsalus and Umbreit (1945) studied the mechanism ...

Robust methods for identifying patterns of expression in genome-wide data are important for generating hypotheses regarding gene function. To this end, several analytic methods have been developed for detecting periodic patterns. We improve one such method, JTK_CYCLE, by explicitly calculating the null distribution such that it accounts for multiple hypothesis testing and by including non-sinus...

The present investigation deals with the formulation of oral dissolving films (ODFs) of sumatriptan succinate which is used for the treatment of migraine. Rapidly dissolving films have acquired great importance in present scenario because of exclusive properties. The films of sumatriptan succinate were carried out using different grades of HPMC E3, E6, and E15, maltodextrin DE6, xanthan gum and...

In this paper, we obtain new bounds for the tensor rank of multiplication in any extension of F2. In particular, it also enables us to obtain the best known asymptotic bound. To this aim, we use the generalized algorithm of type Chudnovsky with derivative evaluations on places of degree one, two and four applied on the descent over F2 of a Garcia-Stichtenoth tower of algebraic function fields d...

To illustrate the construction of precursor complementary DNAs, we isolated mRNAs from whole venom samples. After reverse transcription polymerase chain reaction (RT-PCR), we amplified the cDNA coding for a neurotoxic protein, phospholipase A2 D49 (PLA2 D49), from the venom of Crotalus durissus collilineatus (Cdc PLA2). The cDNA encoding Cdc PLA2 from whole venom was sequenced. The deduced amin...