Process engineers can be faced with the task of understanding and optimizing the performance of an existing liquid-liquid extraction (extraction) column. Often times, an extraction column has been operating many years, and the performance is not well understood by the personnel responsible for its operation. Since this technology is not treated comprehensively during most under-graduate Chemica...

a validated hplc method was developed to determine doxorubicin concentration in a small volume of rat plasma (60 µl) with convenient fluorescence detection. sample preparation includes a simple one-step liquid-liquid extraction using minimum amount of organic solvent, with extraction recoveries more than 95%. the analysis was accomplished using perfectsil c18 column maintained at 35 °c and a mo...

BACKGROUND Extraction of DNA from formalin-fixed, paraffin-embedded (FFPE) tissue is a critical step in molecular oncologic testing. As molecular oncology testing becomes more important for prognostic and therapeutic decision making and tissue specimens become smaller due to earlier detection of suspicious lesions and the use of fine needle aspiration methods for tissue collection, it becomes m...

the mass transfer performance of a pulsed disc and doughnut column for extraction of samarium and gadolinium from aqueous nitrate solution with d2ehpa was investigated. the effects of operating parameters such as pulsation intensity, continuous and dispersed phase velocities on column performance were investigated. the axial dispersion model was used to obtain the overall mass transfer coeffici...

A simple and efficient homogenous liquid-liquid extraction method performed in a narrow tube combined with dispersive liquid-liquid microextraction method has been presented for the simultaneous determination of two antiepileptic drugs in urine followed by gas chromatography with flame ionization detection. In this method, a mixture of acetonitrile and urine sample (homogenous solution) is load...

A simple and efficient homogenous liquid-liquid extraction method performed in a narrow tube combined with dispersive liquid-liquid microextraction method has been presented for the simultaneous determination of two antiepileptic drugs in urine followed by gas chromatography with flame ionization detection. In this method, a mixture of acetonitrile and urine sample (homogenous solution) is load...