Extracellular Vesicles In article number 2211664, Yuehua Liu, Lin Yu, Liming and co-workers, design a hypoxic treatment strategy to increase extracellular vesicles (EVs) production boost their therapeutic efficacy. An injectable bioactive hydrogel is developed improve the in vivo stability retention of EVs, thereby synergistically accelerating bone regeneration. This simple but effective expect...

Mol. Nutr. Food Res. 2023, 67, 2200884 DOI: 10.1002/mnfr.202200884 Extracellular Vesicles (EVs) secreted from probiotics are potential EV-based nanomaterials therapy in inflammatory bowel disease (IBD). Clostridium butyricum-derived extracellular vesicles could be a novel agent for treating colitis and colonic miR-199a-3p might serve as therapeutic target IBD. This is reported by Yingping Xiao ...

Single Extracellular Vesicles Physical and biochemical characterization for single extracellular vesicles (EVs) has been gaining more attention disease diagnosis. With the development of micromachining technologies, microfluidic chips can analyze EVs with precise manipulation, low cost high portability. In foreseeable future, combination microfluidics gradually individualizing them will be a me...

Extracellular vesicles (EVs) secreted by cancer cells play a key role in the microenvironment and progression.

BACKGROUND Extracellular vesicles are lipid bilayer vesicles containing protein, messengerRNA and microRNA. Cancer cell-derived extracellular vesicles may be diagnostic and therapeutic targets. We extracted extracellular vesicles from urine of urothelial carcinoma patients and the control group to identify cancer-specific microRNAs in urinary extracellular vesicles as new biomarkers. MATERIAL...

Extracellular vesicles (EVs) are secreted by cells into the extracellular space, first discovered in 1967 as platelet dust. In recent years, idea that EVs can treat various diseases has emerged studies to understand these vesicles' origin and biological functions. According their size, biogenesis, content, release pathways function, have three main subtypes: microvesicle (MV), exosome (EX) apop...