background petro-clival, clival and spheno-petro-clival tumours are still a neurosurgical challenge. usually, the classical skull base transpetrous approaches are employed, although they are burdened by an important rate of morbidity, and a very low rate of radical removal is reported. conclusions anterior transoral and transsphenoidal approaches are indicated for clival and spheno-petro-clival...

"Tumours of the heart and pericardium have evoked an extensive literature out of all proportion to their uncommon incidence and their relative unimportance as a cause of clinical heart disease." This opening sentence of Friedberg's chapter on cardiac tumours in Diseases of the Heart (Friedberg, 1949) fills a pathologist with diffidence in reporting eight cases that have been seen in the last si...

OBJECTIVE To review the existing literature for evidence that adrenocortical and adrenomedullary tumours develop through a multistep process of carcinogenesis. RESULTS In the adrenal cortex hyperplasia and adenomas are frequently observed tumours or tumour-like conditions. In contrast, adrenocortical carcinomas are rare. Based on well-validated histopathological scoring systems, benign and ma...

Gastrointestinal involvement in neurofibromatosis is well recognised. We present an unusual manifestation of gastro-intestinal neurofibromatosis--chronic gastrointestinal bleeding from extensive smooth muscle tumours.

Basal cell carcinomas of the eyelids, especially those in the medial canthal area, may cause extensive local destruction. Recurrent tumours are more aggressive and become progressively more difficult to treat; this is especially true for postirradiated recurrent, medial canthal, basal cell carcinomas. Tumours in this area should thus be treated by a technique which allows tissue sampling in ord...

ewing sarcoma is about 10 % of bone tumours, in the form of lytic, sclerotic and mixed type. the lytic type erodes the whole bone in such a way that the auther would like to name it 'vanishing' type and recognition of this radiological type is of great importance from differential point of view in the study of primary and secondry tumours of bones.

Mammary sarcomas are heterogeneous group of malignant neoplasms that arise from the mammary stroma. They are uncommon tumours and most of these occur as a component of other tumours. Of the malignant breast mesenchymal tumours, pure sarcomas which lack epithelial component are rarer as these comprise only 0.5% of the breast tumours. Of these, the most common are angiosarcomas, liposarcomas and ...

Many individual primary tumours of the heart have now been reported and there are two general reviews in the English literature, those of Yater (1931) and Prichard (1951), and also an extensive monograph in French by Mahaim (1945). The addition of a few more would be of little interest, but the study of 10 benign tumours, collected from some 19,000 necropsies performed by the staff of a central...