objective: there are few therapeutic options for treatment of multidrug resistant klebsiella pneumoniae isolates as a hospital infectious agent (nosocomial infection). the aim of this study was to evaluate the antibacterial activity of zataria multiflora boiss extracts against esbl-producing klebsiella pneumoniae strains. materials and methods: this study was conducted on 100 k. pneumoniae isola...

conclusions the prevalence of esbl-producing klebsiella strains in shahid-beheshti hospital in kashan has increased. the study concluded that there was a high prevalence of the blactx-m type gene among esbl positive isolates. patients and methods one hundred klebsiella spp. were isolated from clinical specimens of hospitalized patients at shahid-beheshti hospital from december 2012 to november ...

conclusions our study showed that the prevalence of esbl-producing k. pneumoniae at king khalid hospital was significantly high. routine detection of esbl-producing microorganisms is required by each of the laboratory standard detection methods to control the spread of these infections and allow a proper therapeutic strategy. for detection, the phenotypic confirmatory disc diffusion test is sim...

conclusions this study showed that multiple β-lactamases can be produced in burn isolates. this suggests that use of cephalosporins and carbapenems should be restricted in burn isolates to minimize the development and spread of these multidrug resistant pathogens. results there was 99% resistance to carbenicillin, and ticarcillin, 98% to cotrimoxazole, 96% to ciprofloxacin, and aztreonam, 95% t...

  Background and Objective: Organisms producing CTX-M β-lactamases are emerging as a source of resistance to oxyiminocefalosporins such as ceftriaxone and ceftazidime. However, the laboratory detection of these strains is not well defined. In this study, phenotypic assay for screening of extended-spectrum β-lactamases producing strains and molecular assay for the identification of CTX-M β-lact...

conclusions the β-lactamase disk test is appropriately sensitive to detect esbls in mdr isolates of e. coli. background most urinary tract infections (utis) are caused by escherichia coli (e. coli) species. due to infections outbreaks of e. coli strains with multiple mechanisms of resistance to β-lactam antibiotics, the sensitivity of confirmatory tests to detect the extended spectrum β-lactama...