background: despite the effective pre- and post-exposure treatments, at least 60,000 deaths from rabies occur worldwide every year. post-exposure treatment is considered as one of the most significant measures for preventing human deaths in exposed individuals. the 2-1-1 rabies post-exposure treatment schedule known as zagreb regimen is an abbreviated immunization plan in which a tissue culture...

Preexposure prophylaxis (PrEP) and postexposure prophylaxis (PEP) has been shown to be effective in preventing transmission of human immunodeficiency virus (HIV). A dose-response relationship between adherence and HIV transmission is illustrated in the current PrEP literature, and adherence interventions for PrEP may be useful, although currently few effective programs have been developed and t...

Best practices for integrating human immunodeficiency virus (HIV) testing and antiretroviral interventions for prevention and treatment are suggested based on research evidence and existing normative guidance. The goal is to provide high-impact prevention services during periods of substantial risk. Antiretroviral medications are recommended for postexposure prophylaxis (PEP), pre-exposure prop...

Preexposure prophylaxis (PrEP) and treatment as prevention (TasP) involve the use of antiretroviral (ARV) drugs by human immunodeficiency virus (HIV)-negative and -positive individuals to reduce HIV acquisition and transmission, respectively. Clinical science has delivered a consistently high effect size for TasP and a range from 0%-73% reduction in incidence across placebo-controlled PrEP tria...

background: during the one-year period from may 2008 to may 2009, a nationwide shortage developed which rabies vaccine was not being produced by the manufacturers. in order to manage existing supply, a protocol was established wherein an authorization was required from the regional poison center before vaccine could be administered to a patient. methods: the georgia poison center internal datab...

introduction rabies is a fatal disease and has a threatening risk for the public health. immunosuppression is related to a wide variety of diseases. it is recommended that immunosuppressed patients receive the full post-exposure vaccination, concerning that the immune response may be inadequate. the aim of this study is to determine the level of rabies neutralizing antibody in immunosuppressed ...

Disproportionate rates of HIV are observed in Black women and men, especially in the Southern United States. We observed limited uptake of preexposure prophylaxis (PrEP) services in our Southern community among these groups, particularly Black men who have sex with men relative to new HIV cases in Birmingham, AL; 18% accessed PrEP services compared with 50% of new HIV cases. Further research is...

background: the risk for transmission of blood-borne viruses (bbvs) such as human immunodeficiency virus (hiv), hepatitis b virus (hbv) and hepatitis c virus (hcv) due to occupational exposure is a major concern in the health care setting. m aterials and methods: this study among 337 health care workers (hcws) accidentally exposed to bbvs was carried out from january 2009 to march 2015. the dat...

There is a clear convergence toward an overarching strategic use of antiretroviral drugs to prevent human immunodeficiency virus (HIV) infection. Four interventions-immediate antiretroviral therapy (ART) for the infected partner in a serodiscordant couple, preexposure prophylaxis (PrEP), prevention of mother-to-child transmission (PMTCT), and postexposure prophylaxis (PEP)-are all strongly reco...