Diabetes mellitus is a chronic disorder characterized by persistent elevated blood glucose level in the body which leads to various secondary complications like cataract. The understanding of mechanisms exerts its toxicity utmost importance for rational pharmacological interventions treat diabetic Plants have always been an exemplary source drugs and many currently available derived directly or...

Timolol is a non-selective beta-adrenergic receptor antagonist administered for treating glaucoma, heart attacks and hypertension. In the present study, we set out to determine whether or not timolol can provoke cataract formation, thus the influence of timolol on the amyloid-type aggregation of crystallin was investigated. We then provided experimental evidence of crystallin aggregation and it...

PURPOSE In this study, we examined the stability of the lens-angle supporter (LAS) for accommodation restoration by comparing intraocular lens (IOL) location, after-cataract and ciliary body damage after cataract surgery in rabbits. METHODS Eight rabbits were divided into experimental and control groups of four rabbits each. Phacoemulsification and irrigation and aspiration were performed in ...

Cataract is one of the most common eye disorders that causes vision distortion. Accurate and timely detection cataracts best way to control risk avoid blindness. Recently, artificial intelligence-based cataract systems have been received research attention. In this paper, a novel deep neural network, namely CataractNet, proposed for automatic in fundus images. The loss activation functions are ...

THE classical cataract section, either by a von Graefe knife or by a keratome and scissors, is essentially a section in which the cornea is sliced (Fig. 1). An enormous number of techniques has been developed which incorporate this slicing section; these usually involve direct suturing either of the cornea after its section, or of the corneo-scleral margin with or without a flap to cover the in...

Specific areas in carbohydrate and protein metabolism were studied in the lenses of alloxandiabetic rats. The studies were performed at weekly intervals commencing with the first week after diabetes had been induced and continuing until the fourth to fifth week. The results of these investigations indicate that lenticular anaerobic glycolysis as reflected by lactate production and the recovery ...

Cataract is clouding of the eye lens that reduces the amount of incoming light and results in deteriorating vision. Blindness is thought to reach 75 million by 2020. Of these, unoperated cataract may be expected to account for at least 35 million. Thus, the burden of cataract is increasing remorselessly. Embelica officinalis is reported to have a very good antioxidant property and thus we hypot...

A technique to improve an eye cataract early detection and quantitative evaluation of maturity using ultrasound was investigated. A broadband coherent signal, backscattered from an eye lens tissue, was digitized, recorded and processed. A new parameter – lens quality was proposed for the human eye cataract quantitative evaluation. Lens quality reflects two phenomena of ultrasound interaction wi...

Cataract is the leading cause of blindness worldwide. Fortunately, cataract-induced blindness is reversible by cataract surgery. In addition to reclaiming lost vision, cataract surgery lowers intraocular pressure, but the reason for this remains unclear. Understanding the mechanism behind intraocular pressure reduction following cataract surgery has implication for treating glaucoma, which invo...

Previous biochemical and morphological studies with animal experiments have demonstrated that caffeine given topically or orally to certain experimental animal models has significant inhibitory effect on cataract formation. The present studies were undertaken to examine if there is a correlation between coffee drinking and incidence of cataract blindness in human beings. That has been found to ...