نتایج جستجو برای: exotoxin a exoa
تعداد نتایج: 13432061 فیلتر نتایج به سال:
Background: Antibiotic resistance and the need for long-term treatments especially for chronic infections necessitate the development <span style="fon...
Background & Aims: Pseudomonas aeruginosa is an opportunistic pathogen and most important cause of hospital infections, which causes septicemia and death through various virulence factors such as exotoxin A. In the present study, P. aeruginosa exotoxin A (as a toxic factor) was prepared with the aim of obtaining a new recombinant vaccine candidate and conjugated with gold nanoparticles and its ...
Patients with cystic fibrosis (CF) colonized with Pseudomonas aeruginosa (P. aeruginosa) have worse prognosis compared with patients who are not. BPI-ANCA is an anti-neutrophil cytoplasmic antibody against BPI (bactericidal/permeability increasing protein) correlating with P. aeruginosa colonization and adverse long time prognosis. Whether it provides additional information as compared to stand...
مقدمه: pseudomonas aeruginosa از جمله عوامل اصلی عفونت های بیمارستانی است که دارای مقاومت آنتی بیوتیکی و توانایی سازگاری محیطی بالایی است. هدف از انجام این مطالعه، تعیین فراوانی ژن های alg d و exotoxin a (eta) در ایزوله های pseudomonas aeruginosa جدا شده از زخم سوختگی بود. روش ها: در این مطالعه، تعداد 188 نمونه ی جدا شده از زخم سوختگی مورد بررسی قرار گرفت. پس از شناسایی ایزوله های pseudomonas a...
In cystic fibrosis (CF), if Pseudomonas aeruginosa (Pa) infection is not diagnosed and treated early, chronic colonization occurs, which causes rapid decline in pulmonary functions. The aim of this study was to evaluate Pa antibodies, compare them with Pa cultures and determine their role in early diagnosis and follow-up. Ninety CF patients were included; they were divided into chronic, intermi...
سودوموناس آئروژینوزا عامل مهم عفونت بیمارستانی بوده که سپتی سمی ناشی از آن باعث مرگ ومیر زیادی می شود. این باکتری دارای تعداد زیادی از فاکتورهای مقاومت آنتی بیوتیکی با واسطه پلاسمیدوکروموزوم بوده و آنتی بیوتیکهای جدید نیز مرگ و میر ناشی از آن را کاهش نداده اند. به دلیل مقاومت بالا، ایمونوپروفیلاکسی و ایمونوتراپی ممکن است راه موثری برای کنترل و درمان عفونتهای سودوموناس آئروژینوزا در بیماران بستر...
Background and Objective: Antibody against Pseudomonas aeruginosa exotoxin A can be used in immunotherapy together with antibiotics to treat acute burn patients. Exotoxin A is one of the virulence factors in Pseudomonas aeruginosa that comprises of three domains, binding domain, translocation and catalytic domain. The purpose of this study was to produce recombinant domain of the catalytic part...
BACKGROUND Pseudomonas aeruginosa possesses a variety of virulence factors and infections caused by multidrug-resistant P. aeruginosa (MDRPA) in burn patients are a public health problem. OBJECTIVES The aim of this study was to determine the antibiotic resistance pattern, the biofilm formation, the prevalence of MDRPA and two virulence genes (nan1 and exoA) among P. aeruginosa isolated from b...
BACKGROUND Pseudomonas aeruginosa is an opportunistic pathogen that infects patients with cystic fibrosis, burning wounds, ophthalmic traumas and immunodeficiency. OBJECTIVES The aim of the present study was to compare the efficiency of newly designed primer sets with some previously published primers for PCR detection of exoA, oprL and algD genes from P. aeruginosa. MATERIALS AND METHODS A...
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