Exercise-induced bronchospasm (EIB) is acute and reversible airway narrowing that occurs during, and also frequently after, exercise. Because the presenting symptoms of EIB are nonspecific, objective evidence of bronchospasm should be documented to confirm a diagnosis. A 10% or greater decrease in the forced expiratory volume in 1 second (FEV1) from baseline after an adequate exercise challenge...

Sport is an essential part of childhood, with precious and acknowledged positive health effects but the impact of exercise-induced bronchoconstriction (EIB) significantly reduces participation in physical activity. It is important to recognize EIB, differentiating EIB with or without asthma if the transient narrowing of the airways after exercise is associated with asthmatic symptoms or not, in...

OBJECTIVE To compare airway responsiveness to methacholine, cycle ergometer exercise and free running in children with intermittent asthma. METHODS A randomized study was conducted with 30 children of both genders with intermittent asthma. Each child was submitted to challenge testing on three separate days, in random order: a) Methacholine challenge using a dosimeter; b) Exercise challenge t...

BACKGROUND Assess the frequency and severity of exercise-induced bronchospasm (EIB) in obese adolescents. METHODS A cross-sectional descriptive study involving 80 adolescents of both genders, aged 10-16 years-old, divided into four groups according to clinical history of asthma and/or allergic rhinitis and body mass index as follows: asthmatic obese (n = 18); asthmatic non-obese (n = 21); obe...

OBJECTIVE To evaluate effects of overweight on spirometric parameters in adolescents who underwent bronchial provocation test for exercise. METHODS We included 71 male adolescents. The diagnosis of asthma was done based on participants' clinical history and on the International Study Questionnaire Asthma and Allergies in Childhood, and the diagnosis of obesity was based on body mass index abo...

Plasma noradrenaline, adrenaline, and cyclic 3'5' AMP (cAMP) were measured in seven asthmatic patients with known exercise-induced bronchospasm and six matched non-atopic control subjects during a standard treadmill exercise test and then during matched isocapnic hyperventilation. Normal subjects showed a 5.5 fold rise in noradrenaline and a 3.2 fold rise in adrenaline during exercise compared ...