BACKGROUND Ten events per variable (EPV) is a widely advocated minimal criterion for sample size considerations in logistic regression analysis. Of three previous simulation studies that examined this minimal EPV criterion only one supports the use of a minimum of 10 EPV. In this paper, we examine the reasons for substantial differences between these extensive simulation studies. METHODS The ...

The rule of thumb that logistic and Cox models should be used with a minimum of 10 outcome events per predictor variable (EPV), based on two simulation studies, may be too conservative. The authors conducted a large simulation study of other influences on confidence interval coverage, type I error, relative bias, and other model performance measures. They found a range of circumstances in which...

We performed a Monte Carlo study to evaluate the effect of the number of events per variable (EPV) analyzed in logistic regression analysis. The simulations were based on data from a cardiac trial of 673 patients in which 252 deaths occurred and seven variables were cogent predictors of mortality; the number of events per predictive variable was (252/7 =) 36 for the full sample. For the simulat...

The rule of thumb that logistic and Cox models should be used with a minimum of 10 outcome events per predictor variable (EPV), based on two simulation studies, may be too conservative. The authors conducted a large simulation study of other influences on confidence interval coverage, type I error, relative bias, and other model performance measures. They found a range of circumstances in which...

This paper presents methods for improving the attention span of workers in tasks that heavily rely on their attention to the occurrence of rare events. The underlying idea in our approach is to dynamically augment the task with some dummy (artificial) events at different times throughout the task, rewarding the worker upon identifying and reporting them. The proposed approach is an alternative ...

This article presents the Two Variable Per Inequality abstract domain (TVPI domain for short). This so-called weakly-relational domain is able to express systems of linear inequalities where each inequality has at most two variables. The domain represents a sweet-point in the performance-cost tradeoff between the faster Octagon domain and the more expressive domain of general convex polyhedra. ...