OBJECTIVE To evaluate the cytotoxicity and genotoxicity activity of Euphorbia hirta (E. hirta) in MCF-7 cell line model using comet assay. METHODS The cytotoxicity of E. hirta extract was investigated by employing brine shrimp lethality assay and the genotoxicity of E. hirta was assessed by using Comet assay. RESULTS Both toxicity tests exhibited significant toxicity result. In the comet as...

Three new triterpenoids, designated as genicunolide A (1), B (2) and C (3), along with friedelin (4) and friedelinol (5), were isolated from the aerial parts of Euphorbia geniculata. They were characterized as 1β-acetoxy-3β-hydroxy-11α,12α-oxidotaraxer-14-ene, 1β,3β-diacetoxy-21α-hydroxy-11α,12α-oxidotaraxer-14-ene and 3β,9α,20α-trihydroxy-Ψ-taraxast-5-ene, respectively, by spectral and chemica...

The antibacterial activities and phytochemical analysis of crude extracts of four indigenous plants (Acorus calamus, Euphorbia hirta, Solanum surattense and Taxus baccata) grown in Garhwal Hills region of western Himalaya, India were tested against pathogenic Escherichia coli, Staphylococcus aureus, Klebsiella pneumoniae, Staphylococcus epidermidis, and Bacillus cereus. Solvent extraction of in...

Protein hydrolysates prepared from a number of medicinal plants are promising sources of various bioactive peptides. In this work, proteins from dried whole plant of Euphorbia hirta Linn. were extracted and digested with pepsin for 12h. The hydrolysates of lesser than 3 KDa were fractionated by a cut-off membrane. The peptide hydrolysate was then purified by an anionexchange chromatography on D...

The toxic effects of 5 suspected poisonous plants of the genus Euphorbia (Euphorbia balsamifera Aiton, E. heterophylla L., E. hirta L., E. hyssopifolia L., and E. lateriflora Schum and Thonn), which are commonly found in the Nigerian pasture, were evaluated in albino rats using crude aqueous extracts for 14 days. Changes in haematological as well as biochemical parameters were used as indices o...

Euphorbia is a genus of plants belonging to the family Euphorbiaceae. Botanist and taxonomist Carl Linnaeus assigned the name Euphorbia to the entire genus in the physician's honor. Euphorbia hirta is a very popular herb amongst practitioners of traditional herb medicine, widely used as a decoction or infusion to treat various ailments including intestinal parasites, diarrhoea, peptic ulcers, h...

We screened forty crude extracts of twenty commonly used to treat bacterial infections for broad sp more affordable alternative against resistant organisms common pathogenic gram negative and gram positiv diffusion method followed by the tube dilution method extract, Escherichia coli showed sensitivity to zone of inhibition ranging from 7 – 19mm, fifteen Pseudomonas aeruginosa was sensitive to ...

The present study deals with the antimicrobial activity and phytochemical screening of the two medicinal plants, Tinospora cordifolia and Euphorbia hirta those are commonly available in India. Results of antimicrobial activity revealed that these medicinal plant extracts were very effective against Serratia marcescens, E. coli, Streptococcus thermophilus, Fusarium oxysporium, Aspergillus niger ...

molluscicidal activity of different organic solvent extracts of latex of euphorbia pulcherima and euphorbia hirta (family-euphorbiaceae) against two freshwater harmful snails lymnaea acuminata and indoplanorbis exustus has been reported. both the snails are the intermediate hosts of fasciola hepatica and fasciola gigantica, which cause endemic fascioliasis in cattle and livestock of eastern par...