نتایج جستجو برای: ethyl bromopyruvate

تعداد نتایج: 34678  

Journal: :The Journal of biological chemistry 1979
S L Yun C H Suelter

The reaction of bromopyruvate with pyruvate kinase was demonstrated both by noting loss of catalytic activity with time and by incorporation of [14C]pyruvate. The first order rate constant for loss of catalytic activity when plotted as a function of bromopyruvate concentration fit a regular hyperbolic saturation function indicative of the formation of a complex with Ki = 15 mM prior to the inac...

Journal: :international journal of bio-inorganic hybrid nanomaterials 0

mnco2o4 (mno-co2o3) nanocomposite as a binary oxide has been successfully prepared by precipitation method using cobalt nitrate and manganese nitrate as the precursors and then characterized by scanning electron microscopy-energy dispersive micro-analysis (sem-edx) and x-ray diffraction (xrd) techniques. in this work, we report the hydrolysis kinetics reactions of semi mustard (chloroethyl ethy...

Journal: :Cancer research 2014
Frances L Byrne Ivan K H Poon Susan C Modesitt Jose L Tomsig Jenny D Y Chow Marin E Healy William D Baker Kristen A Atkins Johnathan M Lancaster Douglas C Marchion Kelle H Moley Kodi S Ravichandran Jill K Slack-Davis Kyle L Hoehn

Women with metabolic disorders, including obesity and diabetes, have an increased risk of developing endometrial cancer. However, the metabolism of endometrial tumors themselves has been largely understudied. Comparing human endometrial tumors and cells with their nonmalignant counterparts, we found that upregulation of the glucose transporter GLUT6 was more closely associated with the cancer p...

Journal: :The Biochemical journal 1990
K P Williams P F Leadlay P N Lowe

Pyruvate:ferredoxin oxidoreductase and the pyruvate dehydrogenase multi-enzyme complex both catalyse the CoA-dependent oxidative decarboxylation of pyruvate but differ in size, subunit composition and mechanism. Comparison of the pyruvate:ferredoxin oxidoreductase from the protozoon Trichomonas vaginalis and the pyruvate dehydrogenase component of the Escherichia coli pyruvate dehydrogenase com...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه ارومیه - دانشکده شیمی 1392

حفاظت از گروههای عاملی از مراحل اجتناب ناپذیر در سنتز آلی است، در این بین محافظت از گروههای آمینی بسیار حائز اهمیت است. روشهای متعددی از قبیل فرمیله کردن، استیله کردن، محافظت بصورت boc و موارد زیاد دیگری جهت محافظت از گروههای آمینی تاکنون گزارش شده است. از طرف دیگر توسعه و کاربرد کاتالیست ها و حلالهای دوستدار محیط زیست و مزایای واکنشهای بدون حلال همچون سرعت بالای واکنش، خالص سازی آسان، کاهش آلو...

Journal: :Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi 2003
Juan Shi Jishuo Li Yushi Ito Ryuji Inoue

We investigated the possible sources of intracellular ATP which was previously shown essential for maintaining the muscarinic cationic channel activities (or currents; I(cat)) in guinea-pig ileal myocytes, using two variants of patch clamp techniques. Deprivation of external glucose or its replacement with 2-deoxyglucose significantly reduced the magnitude of I(cat), recorded with nystatin-perf...

Journal: :Chemistry & biology 2014
Murat Cokol Zohar B Weinstein Kaan Yilancioglu Murat Tasan Allison Doak Dilay Cansever Beste Mutlu Siyang Li Raul Rodriguez-Esteban Murodzhon Akhmedov Aysegul Guvenek Melike Cokol Selim Cetiner Guri Giaever Ivan Iossifov Corey Nislow Brian Shoichet Frederick P Roth

One drug may suppress the effects of another. Although knowledge of drug suppression is vital to avoid efficacy-reducing drug interactions or discover countermeasures for chemical toxins, drug-drug suppression relationships have not been systematically mapped. Here, we analyze the growth response of Saccharomyces cerevisiae to anti-fungal compound ("drug") pairs. Among 440 ordered drug pairs, w...

2017
Philippe Icard Xiao-Dong Zhang Emilie Varin Stéphane Allouche Antoine Coquerel Maria Paciencia Luc Joyeux Pascal Gauduchon Hubert Lincet Laurent Poulain

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