نتایج جستجو برای: estrogen receptor gene

تعداد نتایج: 1594928  

Journal: :international journal of endocrinology and metabolism 0
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schizophrenia is a debilitating and pervasive mental illness with devastating effects on many aspects of psychological, cognitive and social wellbeing. epidemiological and life-cycle data point to significant differences in the incidence and course of schizophrenia between men and women, suggesting that estrogen plays a “protective” role . adjunctive estrogen therapy has been shown to be effect...

Majidreza Haghzare Marjan Saeedi, Parvaneh Vessal Soheila Nasiri, Zahra Asadi-Kani, Zohreh Tehranchinia

Background: Malignant melanoma is the most aggressive form of skin cancer. In contrast to other tumors, the role of estrogen in the initiation and progression of melanoma remains unclear. The aim of this study was to evaluate estrogen receptor beta protein expression in human melanoma tissues and in the benign melanocytic lesions. Method: Twenty-one patients, 11 with cutaneous melanoma and 10 w...

Journal: :iranian journal of blood and cancer 0
robab sheikhpour hematology and oncology research center, shahid sadoughi university of medical science, yazd, iranسازمان اصلی تایید شده: دانشگاه علوم پزشکی شهید صدوقی یزد (shahid sadooghi university of medical sciences) fatemeh poorhosseini department of immunology, kerman university of medical science, kerman, iranسازمان اصلی تایید شده: دانشگاه علوم پزشکی کرمان (kerman university of medical sciences)

background: breast cancer is the most common cancer in women, containing approximately one third of all illnesses in women. assessment of molecular markers is valuable in predicting the outcome of disease and decision making for optimal treatment. the purpose of this study was to determine the relationship between estrogen and progesterone receptors with her-2, ki67, p53, and clinicopathologica...

Journal: :middle east journal of cancer 0
shilpa garg department of pathology and gynecology, pt. b.d sharma post graduate university of medical sciences, rohtak, haryana, india nisha marwah department of pathology and gynecology, pt. b.d sharma post graduate university of medical sciences, rohtak, haryana, india gulshan chauhan department of pathology and gynecology, pt. b.d sharma post graduate university of medical sciences, rohtak, haryana, india sumiti gupta department of pathology and gynecology, pt. b.d sharma post graduate university of medical sciences, rohtak, haryana, india rajiv goyal department of orthopaedics, pt. b.d sharma post graduate university of medical sciences, rohtak, haryana, india pushpa dahiya department of pathology and gynecology, pt. b.d sharma post graduate university of medical sciences, rohtak, haryana, india

background : this study evaluates estrogen and progesterone expressions in patients with ovarian tumors (both benign and malignant) and their correlation with various clinicopathological prognostic parameters. receptors for estrogen and progesterone are predictive and prognostic markers of endometrial and breast cancers. however, their clinical significance in epithelial ovarian cancer is not c...

Journal: :iranian biomedical journal 0
priyanshee v. gohil saloni p. shah saloni p. shah priyanshee v. gohil gaurang b. shah

background: use of hormone replacement therapy (hrt) may increase the risk of adult-onset asthma in women. various in vitro studies have reported that estradiol stimulates human mast cell lines causing release of allergic mediators which was not observed in estrogen receptor-alpha (er-alpha) knockout mice. thus, estrogen might be a key element in occurrence of asthma. in the present study, we p...

Journal: :مجله زنان، مامایی و نازایی ایران 0
کامران کامران مشفقی kamran moshfeghi assistant professor, department of internal medicine, school of medicine, arak university of medical sciences, arak, iran.استادیار گروه داخلی، دانشکده پزشکی، دانشگاه علوم پزشکی اراک، اراک، ایران.سازمان اصلی تایید شده: دانشگاه علوم پزشکی اراک (arak university of medical sciences) امیر امیر الماسی حشیانی amir almasi hashiani ph.d. student of epidemiology, school of health, arak university of medical sciences, arak, iran.دانشجوی دکتری تخصصی اپیدمیولوژی، دانشکده بهداشت، دانشگاه علوم پزشکی تهران، تهران، ایرانسازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (tehran university of medical sciences) جواد جواد متذکر javad motezaker resident of internal medicine, school of medicine, arak university of medical sciences, arak, iran.دستیار تخصصی داخلی، دانشکده پزشکی، دانشگاه علوم پزشکی اراک، اراک، ایران.سازمان اصلی تایید شده: دانشگاه علوم پزشکی اراک (arak university of medical sciences)

introduction: breast cancer is the most common cancer in women worldwide and her-2 is one importantly prognostic factor in this cancer. tumor markers use as a criterion for predicting recurrence, but in breast cancer physical examination and mammography are important factors that are recommended for following up the recurrence. the aim of this study was to assess the correlation between breast ...

ژورنال: Anatomical Sciences Journal 2011
Mohammadzadeh, Farzaneh, Rastegar , Tayebeh, Eftekharzadeh, Mina, Nobakht , Malihe,

Purpose: The aim of our study is the assesment of estrogen receptor a expression in pyramidal neurons in rat CA 1hippocampus that has been ovariectomized. By using the estrogen antagonist, Tamoxifen level of expression of estrogen receptor a in these cells. Materials and Methods: To study the effect of 17- b estradiol and tamoxifen on estrogen receptors a, expression in hippocampus rats of Wist...

A. K. Goel P. K. Rout S. D. Kharche S. K. Jindal S. Kumar S. Saraswat,

The present study was undertaken to analyze the expression pattern of estrogen receptor 1 gene (ESR1) in Barbari bucks (fertile and non-fertile) identified on the basis of seminal quality traits and fertility trials. RNA was extracted from the spleen by Trizol method. The expression pattern of ESR1 gene was analyzed using real time polymerase chain reaction (RT-PCR). The expression pattern of E...

Alireza Aminzadegan Gholamreza Davoodi Leila Poorgoli Mahboobe Ghaed Mahmood Sheikh Fathollahi, Mohammad Ali Boroumand Narges Mohammad Taghvaie Shekufeh Golkhu,

Estrogen might play an important role in the pathogenesis of diabetes mellitus type 2. Estrogens inhibit diabetes via distinct mechanisms particularly by reducing both hyperglycemia and plasma insulin levels. Estrogen exerts its physiological effects mainly through estrogen receptors including α and β types. Estrogen receptors are found in many tissues that participate in the pathogenesis of ty...

Journal: :Biochemical and Biophysical Research Communications 2021

Estrogen-responsive endometrial cancer (EC) is prevalent in uterine cancer. Its precise molecular mechanisms remain to be elucidated partly because of limited availability estrogen-sensitive EC models recapitulating clinical pathophysiology. We previously established patient-derived cell (EC-PDC) spheroid culture with high expression estrogen receptor α (ERα). Using this EC-PDC, we study the tr...

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