Copper is an essential cofactor for key processes in plants, but it exerts harmful effects when in excess. Previous work has shown that the Arabidopsis (Arabidopsis thaliana) COPT1 high-affinity copper transport protein participates in copper uptake through plant root tips. Here, we show that COPT1 protein localizes to the plasma membrane of Arabidopsis cells and the phenotypic effects of trans...

In this study the influence of copper salts on the hypothalamic ovulatory hormone releasing factor was studied in vivo. 321 healthy adult female rabbits were used. 85 mcg of estradiol-17-beta-benzoate dissolved in 1 ml of sesame oil was injected intramuscularly for 2 days. Absence of ovulation and an active corpus luteum were confirmed by laparotomy. (For the measurement of LH rats were inj...

in order to investigate the effects of piriformospora indica and trichoderma tomentosum fungi on basil (ocimum basilicum l.) growth under copper nitrate levels, a pot experiment in factorial arrangement with three replicates was done during 2012. treatments were four levels of copper nitrate (0, 100, 200 and 300 mg kg-1 of soil) and four levels of fungal coexistence (non-inoculation control, in...

Copper-catalyzed asymmetric allylation of chiral N-tert-butanesulfinyl imines has been described. Dual stereocontrol, through the combination of a chiral auxiliary and a chiral copper complex, has played an important role in achieving the nearly perfect diastereoselectivities (all dr > 99 : 1), especially for ketimine substrates.

Wastewaters containing Cu(II) along with ligands are ubiquitous in various industrial sectors. Efficacy of treatment processes for copper removal, especially precipitation, is greatly debilitated by ligands. Chemical reduction being commonly employed for production of metal nanoparticles has also been used for removing copper. Addition of ammonia was reported to be essential for improving coppe...

Copper is an essential cofactor for many enzymes, and at over a threshold level, it is toxic for all organisms. To understand the mechanisms underlying copper homeostasis of the gram-positive bacterium Bacillus subtilis, we have performed microarray studies under copper-limiting conditions. These studies revealed that the ycnJ gene encodes a protein that plays an important role in copper metabo...

Excessive hepatic copper accumulation occurs in long-lasting cholestatic liver disorders especially in primary biliary cirrhosis. As in Wilson's disease, penicillamine has recently been introduced for the treatment of primary biliary cirrhosis. In Wilson's disease there is decreased biliary excretion of copper. The present study shows that as compared with controls the biliary excretion of copp...

We developed a direct, simple, and sensitive procedure for the simultaneous colorimetric assay of iron and copper in serum, using sodium dodecyl sulfate-ascorbic acid to dissociate iron and copper from transferrin and ceruloplasmin, respectively. We also use a new water-soluble reagent, 2-(5-nitro-2-pyridylazo)-5-(N-propyl-N-sulfopropylamino)phenol disodium salt (nitro-PAPS) and thioglycolic ac...

Established marinas act as gateways for human impact on the natural environment. One of the major ways this occurs is through the leaching of biocides from antifouling paints applied to marine vessels. These paints often contain copper, which can have an effect on non-target organisms, especially those in fouling communities within marinas. In this study, I hypothesized that the level of copper...

The molecular responses of macrophages to copper-based nanoparticles have been investigated via a combination of proteomic and biochemical approaches, using the RAW264.7 cell line as a model. Both metallic copper and copper oxide nanoparticles have been tested, with copper ion and zirconium oxide nanoparticles used as controls. Proteomic analysis highlighted changes in proteins implicated in ox...