An experimental system that permits sensitive and reproducible detection of equine herpesvirus 1 (EHV-1)-specific cytotoxic T-lymphocyte (CTL) activity in the horse was developed. Peripheral blood mononuclear cells (PBMC) collected from immune horses were restimulated in vitro by culture with live EHV-1. Cytotoxic activity against virus-infected, pokeweed mitogen-stimulated lymphoblast targets ...

Intramuscular Immunization of Mice with the Live-Attenuated Herpes Simplex Virus 1 Type-1(HSV-1) Vaccine Strain VC2 Expressing the Equine Herpesvirus-1 (EHV-1) 2 Glycoprotein D (gD) Generates Anti-EHV-1 Immune Responses in Mice 3 4 Shiliang A. Liu, Brent A. Stanfield, Vladimir N. Chouljenko, Shan Naidu, Ingeborg Langohr, 5 Fabio Del Piero, Jacqueline Ferracone, Alma A. Roy, Konstantin G. Kousou...

Incidental findings of virus-like particles were identified following Background: electron microscopy of tissue-engineered tendon constructs (TETC) derived from equine tenocytes. We set out to determine the nature of these particles, as there are few studies which identify virus in tendons , and their presence per se could have implications for tissue-engineering using allogenic grafts. Virus ...

Incidental findings of virus-like particles were identified following Background: electron microscopy of tissue-engineered tendon constructs (TETC) derived from equine tenocytes. We set out to determine the nature of these particles, as there are few studies which identify virus in tendons , and their presence could have per se implications for tissue-engineering using allogenic grafts. Virus p...

Rabbit eyes experimentally infected with either type 1 or type 2 herpes simplex viruses occasionally released virus spontaneously. Injection of adrenalin was not highly effective for stimulating virus release but did seem to have a slight and erratic activating capacity. No spontaneous virus release were detected from the eyes of six cats infected with cat herpesvirus, but, when adrenalin was a...