نتایج جستجو برای: equine antivenom

تعداد نتایج: 14573  

Journal: :Acta tropica 2011
Choo Hock Tan Poh Kuan Leong Shin Yee Fung Si Mui Sim Gnanajothy Ponnudurai Christeine Ariaratnam Sumana Khomvilai Visith Sitprija Nget Hong Tan

Hypnale hypnale (hump-nosed pit viper) is a medically important venomous snake in Sri Lanka and Southwestern India. Bite of this snake may result in hemostatic dysfunction, acute kidney injury and death. Clinical studies indicated that the locally available polyvalent antivenoms produced in India are not effective against hump-nosed pit viper envenoming. Hence, there is an urgent need to search...

Journal: :Clinical toxicology 2016
Nicole M Ryan Renai T Kearney Simon G A Brown Geoffrey K Isbister

CONTEXT Serum sickness is a delayed immune reaction resulting from the injection of foreign protein or serum. Antivenom is known to cause serum sickness but the incidence and characteristics are poorly defined. OBJECTIVE To investigate the incidence and clinical features of serum sickness following the administration of Australian snake antivenoms. MATERIALS AND METHODS This was a prospecti...

2014
Chetanran Ghanshyam Rushikesh Prabhakar

Snake antivenoms are the only definitive management of snake envenoming. Parenteral administration of antivenom mitigates the toxic effects due to snake venom components. However, these benefits come with additional risk of antivenom reactions. The morbidity and mortality of antivenom reactions largely go unnoticed due to lack of awareness and many times these are wrongly attributed to effects ...

2017
Gabriella Neves Leal Santos Barreto Sâmella Silva de Oliveira Isabelle Valle dos Anjos Hipocrates de Menezes Chalkidis Rosa Helena Veras Mourão Ana Maria Moura-da-Silva Ida Sigueko Sano-Martins Luis Roberto de Camargo Gonçalves

Bothrops atrox snakes are the leading cause of snake bites in Northern Brazil. The venom of this snake is not included in the antigen pool used to obtain the Bothrops antivenom. There are discrepancies in reports on the effectiveness of this antivenom to treat victims bitten by B. atrox snakes. However, these studies were performed using a pre-incubation of the venom with the antivenom and, thu...

2017
G. K. Isbister S. Jayamanne F. Mohamed A. H. Dawson K. Maduwage I. Gawarammana D. G. Lalloo H. J. de Silva F. E. Scorgie L. F. Lincz N. A. Buckley

Essentials Russell's viper envenoming is a major health issue in South Asia and causes coagulopathy. We studied the effect of fresh frozen plasma and two antivenom doses on correcting coagulopathy. Fresh frozen plasma did not hasten recovery of coagulopathy. Low-dose antivenom did not worsen coagulopathy. SUMMARY Background Russell's viper (Daboia russelii) envenoming is a major health issue ...

2014
Toru Hifumi Atsushi Sakai Akihiko Yamamoto Masahiro Murakawa Manabu Ato Keigo Shibayama Hiroshi Kato Yuichi Koido Junichi Inoue Yuko Abe Kenya Kawakita Masanobu Hagiike Akihiko Ginnaga Yasuhiro Kuroda

BACKGROUND Rhabdophis tigrinus (Yamakagashi snake) is a rear-fanged colubrid snake present throughout Russia and Asia. Its venom induces life-threatening hemorrhagic symptoms and severe disseminated intravascular coagulation with a fibrinolytic phenotype. R. tigrinus antivenom manufactured by the immunization of horses to neutralize the venom has the risk of adverse events such as anaphylaxis a...

Journal: :The American journal of tropical medicine and hygiene 2005
Harold Merle Angélique Donnio Lucas Ayeboua Yves Plumelle Didier Smadja Laurent Thomas

We report a case of snakebite in which envenomation was manifested through impairment of the visual field. The patient, a 46-year-old man, was bitten on the right thumb by Bothrops lanceolatus. Treatment with a specific equine antivenom (Bothrofav) was administered one hour after the bite. With the exception of fang marks, the results of a clinical examination, particularly the neurologic compo...

Journal: :Toxicon : official journal of the International Society on Toxinology 2013
Salvatore G De-Simone Paloma Napoleão-Pego Luiz A L Teixeira-Pinto Jonathas D L Santos Thatiane S De-Simone Anibal R Melgarejo Aniesse S Aguiar Daniela P Marchi-Salvador

The benefits from treatment with antivenom sera are indubitable. However, the mechanism for toxin neutralization has not been completely elucidated. A mixture of anti-bothropic and anti-crotalic horse antivenom has been reported to be more effective in neutralizing the effects of Bothrops jararacussu snake venom than anti-bothropic antivenom alone. This study determined which regions in the thr...

Journal: :Acta tropica 2015
Poh Kuan Leong Shin Yee Fung Choo Hock Tan Si Mui Sim Nget Hong Tan

The low potency of cobra antivenom has been an area of concern in immunotherapy for cobra envenomation. This study sought to investigate factors limiting the neutralizing potency of cobra antivenom, using a murine model. We examined the immunological reactivity and neutralizing potency of a Thai polyvalent antivenom against the principal toxins of Naja sumatrana (Equatorial spitting cobra) veno...

Journal: :Australian Prescriber 2013

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