background: the association of epstein-barr virus (ebv) with burkitt’s lymphoma (bl) is variable in different geographic regions. in developing countries, the association of ebv with bl is regarded to be of an endemic-type in equatorial africa ( > 95%) and sporadic-type in the developed countries (15-30%). the purpose of this study is to assess the frequency of ebv infection in bl, in iran. the...

the aim of this work was to see whether tamarin immunisation with recombinant vaccinia virus expressing epstein barr virus latent proteins could prime t cells which were, on activation, able to inhibit the outgrowth of epstein barr virus transformed cells in vitro. the vaccination appeared to be successful as all vaccinated tamarins developed vaccinia lesions. however, the vaccination protocol ...

hemophagocytic lymphohistiocytosis (hlh) is one of the complications of epstein-barr virus (ebv) infection. although the patients who have developed hlh following ebv have normal immune system, there are a few patients with ebv-induced immune deficiency who develop hlh as well. here, we describe the case of a 10-year-old girl with neurological complications caused by ebv-induced hlh. the patien...

Background: Breast cancer is the malignancy in humans and other mammals. Several risk factors are involved in their appearance such as higher hormone levels and obesity. Identification of a mouse mammary tumor virus supports a viral etiology for breast tumors in animals. Viruses have been implicated in the development of various cancers, but viral induction for formation breast cancer is contro...

Background: environmental factors may play a role in colon cancer. In this view, several studies investigated tumor samples for the presence of various viral DNA with conflictiong results.  The purpose of this study is to investigate the prevalence of Human papillomaviruses (HPVs) and Epstein–Barr virus (EBV) in patients with colorectal carcinomas. Materials and methods: In this  study, we co...

background epstein-barr virus (ebv) is a dna virus which belongs to the herpesviridae family and in γ-herpesvirus subfamily, has been infected about 95% of the world’s population. ebv is transmitted through saliva and associated with different disease such as infectious mononucleosis, nasopharyngeal carcinoma, burkitt`s lymphoma, hodgkin and non-hodgkin`s lymphoma. the study proposed to determi...

background: breast cancer is the most common malignancy in females worldwide. several etiological factors including environmental factors have been recognized for breast cancer. epstein barr virus as a viral etiological factor has been proposed. so far, several studies have investigated the relationship between development of breast cancer and epstein barr virus, but few have been done in iran....

background epstein barr virus (ebv) is one of the most common viral infections in human population. ebv has a significant role in pathogenesis of hodgkin's lymphoma, burkitt's lymphoma and nasopharyngeal carcinoma. the role of ebv in non-hodgkin’s lymphoma, diffuse large b cell (nhl - dlbl) in the head and neck is controversial. objectives the purpose of this study is to find out the ...

Lymphoproliferative disorders following liver transplantation are often Epstein-Barr virus (EBV)-related highgrade B cell lymphomas. EBV-negative and low-grade lymphoma is a very rare condition after cadaveric as well as living donor liver transplantation (LDLT). Herein we report a case of follicular lymphoma with negative EBV viral capsid antigen (VCA), IgM, IgG and Epstein-Barr virus-encoded ...