Keratoconus and other corneal conditions associated with progressive stromal thinning including keratectasia after laser-assisted in situ keratomileusis (LASIK) and pellucid marginal degeneration represent therapeutic challenges. Until recently, available therapies including contact lenses, epikeratoplasty, intrastromal corneal rings, and corneal transplantation targeted, in principle, the abno...

BACKGROUND A new technique, therapeutic alloplastic laser in situ keratomileusis to correct high myopia, is introduced. METHODS Therapeutic alloplastic laser in situ keratomileusis consists of neutral homoplastic epikeratoplasty combined with superficial keratectomy performed with an excimer laser and/or a microkeratome. Indications for the technique are: myopia over 20 diopters (D), eyes wit...

Background: Keratoglobus is a rare noninflammatory corneal disorder characterized by diffuse corneal thinning and globular protrusion of the cornea. Surgical management of keratoglobus is challenging and the standard method has not yet been defined. Aim: To present the role of large penetrating keratoplasty (PK) in the management of keratoglobus. Case Presentation: A 29-year-old male patient wi...