نتایج جستجو برای: epigenetic modification
تعداد نتایج: 162408 فیلتر نتایج به سال:
Based on the analysis of 20 different monocot and eudicot species, we propose that the centromeric distribution of the phosphorylated histone H2AThr120 is evolutionary highly conserved across species with monoand holocentric chromosomes. Therefore, antibodies recognizing the phosphorylated threonine 120 of the histone H2A can serve as a universal marker for the cytological detection of centrome...
Epigenetic modification is one of the effective factors in tumorigenesis. Epigenetic processes, especially aberrant DNA methylation, play important role in thyroid cancer, and many tumor suppressor genes including PTEN, RASSF1A and TIMP3 are aberrantly methylated and silenced in thyroid cancer. Because of the specified pattern of DNA methylation in various tumor cells, it is suggested that thes...
objective: in about 50% of infertile couples a male factor can be found to be present either alone or in addition to other female factors. a new molecular mechanism recently revealed to be involved in infertility is epigenetic pattern modification like as aberrant methylation. this mechanism can change or even silence gene expression. on the other hand, gstm1 (glutathione s-transferase mu 1) ...
Aging is the outcome of the progressive accumulation of different alterations in the body which accompanied with gradual decrease of the efficiencies of normal physiological functions and the capacity to maintain homeostasis that lead to the increase in disease probability and the death of people. The researchers have done different experiments especially on animal models for the perception of ...
BACKGROUND Pituitary adenomas (PAs) are commonly occurring neoplasms with diverse endocrine and neurological effects. Although somatic gene mutations are uncommon in sporadic PAs, recent studies lend support to epigenetic modification as a potential cause of tumorigenesis and tumor progression. METHODS A systematic literature review of the PubMed and Google Scholar databases was conducted to ...
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