Effect of melatonin, testosterone and of both hormones given in parallel on rat epididymis was tested in rats given a single dose of 1 mg stilbestrol on the first day of the life. The hormones were given daily for 39 days, beginning from the 20th or 28th day of life. The single dose of estrogen treatment resulted in epididymis atrophy, accompanied by changes in glandular epithelium and in its s...

As part of our efforts to identify novel contraceptive targets in the epididymis we performed transcriptional profiling on each of the 10 and 19 segments of the mouse and rat epididymidis, respectively, using Affymetrix whole genome microarrays. A total of 17 096 and 16 360 probe sets representing transcripts were identified as being expressed in the segmented mouse and rat epididymal transcrip...

background: about 90% of the world�s contraceptive users are women. this gender-based usage has occurred due to the emphasis of family planning programs and contraception research. condom, vasectomy and withdrawal are the only male contraception devices available with less assurance for men. for new male contraceptive to have an impact, they must be acceptable to both men and women, as well as ...

Compared to other animals, the anatomy of the human epididymis appears unusual. The caput epididymis is composed mostly of efferent ducts with an undefined initial segment. The present study investigates the regionalization of c-ros in human epididymis by real-time quantitative RT-PCR, in situ hybridization and immunohistochemistry studies. C-ros gene encodes a receptor-type protein tyrosine ki...

Aim: The current study investigated the anti-oxidant effects of vitamins on lead-induced reproductive toxicity in male wistar rats.
 Study Design: A total 48 Wistar rats divided into 6 groups 8 per group were used this study. Group 1 served as positive control and was given normal animal feed water ad libitum. 2 negative administered 10mg/kg body weight lead acetate (Pb) only, 3 with 200mg...

The epididymis is the site for the transport, maturation, and storage of spermatozoa. Regulation of epididymal structure and function is highly dependent on the ipsilateral testis. At the molecular level, however, few studies have been undertaken to determine which genes are expressed in the epididymis under testicular regulation. The goal of this study was to identify genes for which expressio...

This report concerns the case of an unusual tumour of the epididymis, i.e. a haemangioma. This led to secondary extensive bleeding and haemorrhagic infarcting of the testis and the epididymis. Frequency, diagnosis, differential diagnosis, therapy and prognosis of the tumours of the epididymis are also discussed.

OBJECTIVES Patients with idiopathic chronic scrotal pain are challenging to both the general practioner and urologist. In this study, we tried to recognize mild epididymitis as an underrecogniczed cause of idiopathic chronic scrotal pain. Methods : We described a consecutive series of 44 patients with idiopathic chronic scrotal pain characterized by mild scrotal pain, mild to moderate tendernes...

Recently we reported that mouse germ cells in the testis contain active P450 aromatase (P450arom), the enzyme that converts androgens to estrogens. This finding suggested that germ cells have the ability to produce estrogen. Further studies have shown that germ cells in the testis of several species contain P450arom. The goal of this study was to determine if epididymal sperm contain P450arom a...

Background: High content of phospholipids in testes and epididymis is involved in regulation of spermatogenesis. On the other side, it makes testes susceptible to oxidative stress due to lipid peroxidation, which alters the normal mechanism of spermatogenesis. Objective: In the present investigation, antioxidant effects of ethanolic extracts of parsley, lettuce and brahmi were tested against D-...