we report a rare, severe case of traumatic globe avulsion and its assessment and management. a 60-year-old man was presented with complete globe avulsion following a facial trauma. left globe was luxated out of the orbit. no direct or indirect light reflexes or any eye movement could be noted. ct-scan showed complete laceration of the left optic nerve, globe protrusion and multiple orbital bone...

PURPOSE Holmium laser enucleation of the prostate (HoLEP) is known to have a steep learning curve and, as a result, its clinical usage has limitations. The purpose of this study was to analyze the learning curve and early complications following the HoLEP procedure. MATERIALS AND METHODS A retrospective analysis was performed on 161 patients who had undergone the HoLEP procedure for lower uri...

BACKGROUND Choroidal malignant melanoma is a rare intraocular cancer in Asian Indian population. There is a paucity of data from our population comparing iodine 125 (I-125) brachytherapy and enucleation. AIM This study aims to compare two groups of choroidal melanoma patients treated with either I-125 brachytherapy or enucleation in the Asian Indian population. OBJECTIVES To evaluate the lo...

BACKGROUND We investigated the contributing causes and factors leading to eye enucleation procedure among the patients referred to the ophthalmology clinic of the Center Eye Hospital in Tehran, Iran. PATIENTS AND METHODS We retrospectively analyzed the clinical records of patients referred to the ophthalmology clinic of the Center Eye Hospital in Tehran, Iran, in the past 3 years. The data re...

Background: The oocyte is a unique cell committed to reprogram fertilizing sperm and to support early stages of embryonic development until the species-specific stage of zygote genome activation that occurs around the second to third cell cycle in sheep embryos. In this sense, considering the huge list of oocyte transcripts, we selected some candidates genes based on their roles of regulating di...

Mammalian erythroblasts undergo enucleation, a process thought to be similar to cytokinesis. Although an assemblage of actin, non-muscle myosin II, and several other proteins is crucial for proper cytokinesis, the role of non-muscle myosin II in enucleation remains unclear. In this study, we investigated the effect of various cell-division inhibitors on cytokinesis and enucleation. For this pur...

OBJECTIVE To evaluate whether the removal of the eye after radiotherapy alters the rates of metastatic death in patients with melanoma of the choroid. PATIENTS AND METHODS Using an extension of the Cox model, we based our analysis on a cohort of 1541 consecutive patients with unilateral choroidal or ciliary body melanoma treated with protons (70 cobalt-gray equivalent in 5 to 7 fractions) at ...

BACKGROUND During the final stages of differentiation of mammalian erythroid cells, the chromatin is condensed and enucleated. We previously reported that Rac GTPases and their downstream target, mammalian homolog of Drosophila diaphanous 2 (mDia2), are required for enucleation of in vitro cultured mouse fetal liver erythroblasts. However, it is not clear how chromatin condensation is achieved ...

Objective: Although morcellation is a standard procedure of Holmium Laser Enucleation the Prostate (HoLEP), studies on morcellators used are limited in number. We aimed to compare two different tissue HoLEP, which have similar objectives but differences efficiency and safety working principles. Material Methods: The data 130 patients who underwent HoLEP between December 2018 2019 were retrospec...