The early effect of intravenous Digoxin was observed in 12 patients with cardiac enlargement in whom there was no clinical or physiologic evidence of failure. There was either a fall or no change in the cardiac output and the intracardiac pressures did not alter following administration of the drug. The reaction to Digoxin in this type of patient with heart disease was in no way different from ...

primary pleuropulmonary synovial sarcomas are rare soft tissue malignancies; combined metastatic involvement of the heart is extremely rare. in this case report, a 17-year-old female presented with a history of chest pain. chest radiographs revealed a round mass in the left upper hemithorax, and computed tomography (ct) showed a well-defined heterogeneous enhancing mass abutting the pleura. a c...

From the *Department of Paediatrics, Division of Paediatric Cardiology, London Health Sciences Centre, London, Ontario, Canada; †Labatt Family Heart Centre, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada; and the ‡Department of Paediatric Cardiology and Intensive Care Medicine, Medical School Hannover, Hannover, Germany. Manuscript received May 31, 2011, accepte...

The distance from the midline to the left heart border measured in a standardized manner on calibrated chest roentgenograms was determined serially in 125 patients after acute myocardial infarction. This external left heart dimension (LHD) was compared to the normal value, and its prognostic value was assessed during early and late follow-up periods (average 10, range 2-31 months). Within 96 ho...

Background Ebstein’s anomaly of the tricuspid valve involves a congenitally displaced and dysplastic tricuspid valve (TV). The displacement of the TV towards the apex results in an enlarged right atrium (RA) with an atrialzied portion of the right ventricle (aRV) and an enlarged functional right ventricle (fRV). Brain natriuretic peptide (BNP) is a heart failure marker. Its role in Ebstein’s an...

Because it is safe and well tolerated, imatinib is a standard first-line therapy for chronic myeloid leukemia (CML). Although there have been sporadic reports of imatinib-induced cardiotoxicity, including left ventricle (LV) dysfunction and heart failure, the evidence for it is contradictory. Here, we reported a case of an 88-year-old male patient with CML developed decompensated heart failure ...

PATIENT Female, 62 FINAL DIAGNOSIS: Tricuspid regurgitation Symptoms: Dyspnea exertional • fatigue • leg edema MEDICATION - Clinical Procedure: - Specialty: Cardiology. OBJECTIVE Challenging differential diagnosis. BACKGROUND Tricuspid regurgitation (TR) can mimic some hemodynamic findings of constrictive pericarditis (CP), due to the restraining effect of the enlarged right heart on inta...

We have studied four hearts in which enlargement of the ventricular membranous septum was associated with histological abnormalities of the atrioventricular conduction tissues. Two of the cases showed unusually formed penetrating and non-branching main atrioventricular bundles. These two cases plus one other also showed right-sided penetrating and main atrioventricular bundles. In addition thes...

Background The athlete’s heart is physiologically enlarged with an extraordinary ability to pump large volumes of blood at high heart rates. We hypothesized that efficient filling and emptying is related to the kinetic energy (KE) of intra-cardiac blood. Therefore, the aim of this study was to investigate variations in KE in the four chambers of the heart over the cardiac cycle and compare endu...