Central vein stenosis is a well-documented consequence of cardiovascular implantable electronic devices. In hemodialysis patients, where preserving venous real estate is crucial, use of subcutaneous implantable cardioverter-defibrillators (S-ICDs) remains controversial. We present a novel approach for implanting an S-ICD in a patient with endstage renal disease, central venous stenosis, and pre...

More than 30 years ago diabetic patients with endstage renal disease (ESRD) were considered as inappropriate candidates for a chronic dialysis programme because of a very high mortality rate and poor longterm survival w1x. In spite of this negative attitude against diabetics on dialysis, not only more and more diabetic patients have been accepted to chronic renal replacement therapy, but diabet...

Autosomal dominant polycystic kidney disease (ADPKD) is generally a late-onset multisystem disorder characterized by: bilateral renal cysts; cysts in other organs including the liver, seminal vesicles, pancreas, and arachnoid membrane; vascular abnormalities including intracranial aneurysms, dilatation of the aortic root, and dissection of the thoracic aorta; mitral valve prolapse; and abdomina...

Fourteen percent of deaths among patients with endstage kidney disease (ESKD) are due to infections, preceded only by cardiovascular diseases (USRDS,2006). According to The United States Renal Data System (USRDS), the number of patients receiving hemodialysis in the United States of America (USA) was 328,000 in 2006(USRDS,2008). Secondary to multiple defects in the ability to kill bacteria, inf...

1. Lysaght MJ. Maintenance dialysis population dynamics: Current trends and long-term implications. J Am Soc Nephrol 2002; 13: S37–S40 2. Parker F, Blantz R, Hostetter T et al. Chronic Kidney Disease initiative. J Am Soc Nephrol 2004; 15: 708–716 3. Xue JL, Ma LZ, Louis TA et al. Forecast of the number of patients with the endstage renal disease in the United States. Am J Kidney Dis 2001; 12: 2...

Familial juvenile hyperuricaemic nephropathy (FJHN; OMIM 162000) is considered a rare cause of endstage renal disease (ESRD). FJHN is characterized by hyperuricaemia and gout after adolescence and the slow development of renal insufficiency, leading to ESRD in adulthood. The disorder is characterized by a renal under-secretion of urate, which may be detected already during early childhood [1]. ...