OBJECTIVE We evaluated postoperative changes in nasal cavity volume and their effects on nasal function and symptoms after endoscopic endonasal transsphenoidal approach for antero-central skull base surgery. STUDY DESIGN Retrospective chart review at a tertiary referral center. METHODS We studied 92 patients who underwent binostril, four-hand, endoscopic endonasal transsphenoidal approach s...

OBJECTIVES/HYPOTHESIS Olfactory disturbances could be observed following transsphenoidal pituitary surgeries. To our knowledge, no previous comparative studies on olfactory functions after transsphenoidal endoscopic and microscopic approaches have been performed. STUDY DESIGN Prospective study comparing olfactory functions between endoscopic and microscopic transsphenoidal pituitary surgery. ...

Objective: This study aims to analyze the complications of endoscopic transsphenoidal surgery for pituitary neoplasms. Methods: 326 patients who underwent neuroendoscopic endonasal transsphenoidal surgery at the neurosurgery department of the First Affiliated Hospital of Chongqing Medical University from July 2012 to July 2015 were enrolled in this retrospective analysis. Results: Among the 326...

Introduction: The endoscopic transsphenoidal approach for pituitary adenomas and other sellar lesions is quickly becoming the procedure of choice in their surgical management. The most common approach is binostril three-hand technique which requires a large exposure and subjects both nasal cavities to potential trauma. To reduce nasal morbidity, we employ a mononostril two-hand technique with t...

BACKGROUND Olfaction has been demonstrated to have a great impact on patients' lives. Transsphenoidal endoscopic pituitary surgery is associated with potentially significant damage to olfactory tissues, but to date this issue has been only poorly documented in the literature. STUDY DESIGN Prospective cohort study comparing olfactory outcomes pre- and postpituitary surgery. METHOD Patients w...

Background: Currently, transsphenoidal surgery is considered the procedure of choice for treating most sellar lesions. There are two different surgical options for performing the transsphenoidal procedure, the transseptal and the endonasal techniques. Objective: the aim of this study is to compare transseptal and endonasal approaches in endoscopic transsphenoidal surgery for pituitary tumors re...

OBJECTIVE The aim of this study was to describe the use of equine pericardium sheet (Lyomesh (®) ) as dural substitute for sellar reconstruction after endoscopic endonasal transsphenoidal surgery for the removal of pituitary adenomas. METHODS We reviewed data of patients that underwent surgery by means of an endoscopic endonasal transsphenoidal approach for the removal of pituitary adenomas o...