background: endometriosis is one of the most commonly encountered benign problems in gynaecology. it is frequently associated with chronic pelvic pain, dysmenorrhoea, menorrhagia and dyspareunia, which lead to infertility. we determined the possible association between cyp1a1 mspi and gstm1 null polymorphism in the pathogenesis of endometriosis. materials and methods: ninety seven cases of endo...

background: endometriosis is a common chronic inflammation causing major problems including infertility. the role of omega-3 and omega-6 fatty acids as their potential anti-inflammatory effects in endometriosis needs to be further explored. the objective of this study was to compare serum phospholipid fatty acid profile in endometriosis patients with controls, and to explore the correlation of ...

BACKGROUND Initial publications examining the hereditary aspects of endometriosis appeared in the early seventies and demonstrated an up to seven-fold risk for endometriosis in first-degree relatives of endometriosis patients. The aim was to evaluate the influence of hereditary aspects on the endometriosis risk in our patient collective. METHODS In a retrospective cohort study we evaluated th...

Previous studies have demonstrated the involvement of nerve repellent factors in regulation of the imbalanced innervation of endometriosis. This prospective study aims to explore the role of Sema 3A in regulating aberrant sympathetic innervation in peritoneal and deep infiltrating endometriosis. Ectopic endometriotic lesion were collected from patients with peritoneal endometriosis (n = 24) and...

Definitive risk factors for endometriosis remain unknown due to the lack of knowledge concerning the pathogenesis of the condition, and little research has evaluated endometriosis within the adolescent population. The purpose of this cross-sectional descriptive study was to compare the exercise habits, cigarette smoking, alcohol consumption, and caffeine intake between adolescent girls with and...

results totally, 101women were evaluated during the study. endometriosis was present at laparoscopy in 58 patients. mean age and the duration of infertility were calculated 30.78 ± 4.79 and 4.2 ± 2.91 years respectively. frequencies of each sonographic finding were as follow: echogenic points (%31.68), ovarian endometrioma (%30.69), blurred ovary margin (%7.92), fixation of ovaries (%15.9), dev...

Background: Endometriosis is a chronic inflammatory disease with the growth of endometrial cells out of uterus and in the peritoneal cavity. T cell subsets participate in the establishment and progress of the disease by producing different cytokines. Objective: To investigate a group of cytokines related to Th1/Th2/Th17/Treg subsets within both peripheral blood...

Cutaneous endometriosis represents a non-neoplastic, ectopic growth of endometrial glands and stroma outside the uterine cavity [1-4]. Daneil Schroen, a German physician, first described endometriosis in 1690 [5]. Years later, in 1885, the first case of cutaneous endometriosis was identified and reported [3]. Cutaneous endometriosis is typically divided into two categories, scar endometriosis a...

Objective: Endometriosis, one of the most common estrogen dependent gynecological disorders, can present as both benign and malignant disease. The prevalence of tumoral transformation is 0.7-1.6% and the most common tumors are clear cell and endometrioid carcinomas. Unfortunately, the pathogenesis of transformation is unknown. For this purpose, we examined molecular alterations in ovarian endom...

INTRODUCTION Endometriosis is defined as overgrowth of endometrial tissue outside the uterine cavity. Endometriosis may be asymptomatic or associated with dysmenorrheal symptoms, dyspareunia, pelvic pain, abnormal uterine bleeding and infertility. The aim of this study was to explore the risk factors related to endometriosis among infertile Iranian women. MATERIAL AND METHODS In this case con...