The thyroid gland-iodine connection was known just a few years following the discovery of iodine in seaweed in the 1811. Only 8 years after this discovery, iodine was used effectively in the treatment of simple goiter. However, the medical uses of iodine during the first century since the discovery of iodine were not restricted to diseases of the thyroid gland only but covered a wide range of c...

BACKGROUND In Iran, an iodine deficiency control program was initiated in 1989 by iodizing salt. Despite this program, goiters have remained an endemic condition in most parts of Iran. Thus, it is possible that other factors aside from iodine deficiency may contribute to endemic goiter. The aim of this study was to investigate the association between cobalt deficiency and endemic goiter in a re...

OBJECTIVES To report a new phenotype of advanced endemic goiter that affects only one lobe of the thyroid gland. PATIENTS AND METHODS This study included 60 patients from the west of Sudan with long-standing unilateral simple endemic goiter that required obectomy, with emphasis on the gross appearance, measurements and cytological features of the contralateral lobe. RESULTS Out of 60 patien...

The mountain slopes of the Himalayas, Alps, Pyrenees, and Andes have been the world’s most notorious foci of endemic goiter (1). The northern frontiers of India extending from Kashmir in the west to Assam in the east form an extensive Himalayan goiter belt (2). Forty million persons are believed to be exposed to the risk ofgoiter in this belt and approximately nine million are afflicted with it...

“Goiter” means thyroid enlargement, and “endemic” means frequent in a certain locality. The problem is from what volume and up a thyroid is considered to be large enough as to be classified as goiter and also from what prevalence and up an area is considered to be endemic. It is obvious that by playing with these definitions one may increase or decrease the prevalence of goiter perceived in an ...

The main objective of this study was to assess the iodine nutritional status among school children (6-12 yrs) of Sundarban delta in North 24-Parganas district of West Bengal in eastern India. A total of 2050 children were clinically examined for goiter and 240 urine samples were analyzed for iodine and thiocyanate respectively; iodine content in 48 water samples and 210 salt samples were also m...

The objectives of the present study were to investigate the prevalence of histologic thyroids lesions and the respective thyroid hormones changes of ewes in an endemic goiter region and to find out any impact of this condition on the fetal thyroid structures and serum thyroid hormones. In the present study a total number of 100 pregnant ewes and their fetuses slaughtered at slaughterhouse were...