Legislation from 2015 that sought to repeal core provisions of the ACA but was not ultimately enacted is a starting point for considering the future of the ACA. The legislation would have repealed multiple parts of the statute, including the individual mandate, the premium tax credit, the Medicaid expansion, the employer mandate, and various taxes enacted under the ACA. The 2015 legislation did...

Cytochrome P450 (P450) induction is often considered a liability in drug development. Using calibration curve–based approaches, we assessed the induction parameters R3 (a term indicating the amount of P450 induction in the liver, expressed as a ratio between 0 and 1), relative induction score, Cmax/EC50, and area under the curve (AUC)/F2 (the concentration causing 2-fold increase from baseline ...

PURPOSE The main goal of the current research was to investigate whether and how leaders in health care organizations can stimulate incident reporting and error management by "walking the safety talk" (enacted priority of safety). DESIGN/METHODOLOGY/APPROACH Open interviews (N = 26) and a cross-sectional questionnaire (N = 183) were conducted at the Rotterdam Eye Hospital (REH) in The Netherl...

To determine the nationwide status of persistent BVDV infection in different bovine species in China and compare different test methods, a total of 1379 serum samples from clinical healthy dairy cattle, beef cattle, yaks (Bos grunniens), and water buffalo (Bubalus bubalis) were collected in eight provinces of China from 2010 to 2013. The samples were analyzed using commercial antibody (Ab) and ...

The Effectiveness of Policies that Promote Labor Force Participation of Women with Children: A Collection of National Studies Numerous countries have enacted policies to promote the labor force participation of women around the years of childbearing, and unsurprisingly, many research articles have been devoted to evaluating their effectiveness. Perhaps more surprisingly, however, six such artic...

The inclusion of articles on reproduction technology (RT) in this issue of the Hong Kong Medical Journal is timely, because legislation to control infertility treatments using such technology was enacted during the most recent session of the Legislative Council in Hong Kong. The next step will be the formation of a Council on Human Reproductive Technology, which will put this legislation into p...