Ellipsoid-shaped nanoclusters composed of single superparamagnetic nanoparticles can be generated by emulsion electrospinning. Stretching and subsequent solvent evaporation of iron oxide loaded emulsion droplets during the emulsion electrospinning process enables the creation of such structures embedded in polymer nanofibers. Dissolution of the polymer fibers yields an aqueous dispersion of the...

Floating drug delivery systems are mainly expected to remain buoyant in gastric contents and consequently enhance the bioavailability of drugs Microsphere is loaded with a their outer polymer shells was prepared by novel emulsion-solvent diffusion method. It floated continuously over surface acidic dissolution media containing surfactant for invitro time 12 hours. microspheres ofloxacin were o/...

Nanoparticles were obtained by nanoprecipitation and emulsion solvent evaporation (ESE) method. In the ESE method, size of particles depended on type concentration surfactant (in water phase) polymer organic phase). The best results with ionic surfactants, however, use such compounds may accelerate degradation process polymers. ratio (methylene chloride) to non-solvent (hexane) has a significan...

the present study involves preparation and evaluation of gastric-mucoadhesive microparticles with metformin hydrochloride as model drug for prolongation of gastric residence time. the microparticles were prepared by the emulsification solvent evaporation technique using polymers of carbomer 934p (c) and ethylcellulose (ec). the microparticles were prepared by emulsion solvent evaporation method...

Biodegradable poly(D, L-lactide-co-glycolide) (PLGA) and PLGA-based polymeric nanoparticles are widely used for sustained release of protein and peptide drugs. These formulations are usually prepared by water/oil/water (W/O/W) and solid/oil/water (S/O/W) double emulsion solvent evaporation method. Other methods of preparation are nanoprecipitation, emulsion solvent diffusion and salting-out. Th...

Nanoparticles formulated from biodegradable polymers like poly(lactic-co-glycolic acid) (PLGA) are being extensively investigated as drug delivery systems due to their two important properties such as biocompatibility and controlled drug release characteristics. The aim of this work to formulated diazepam loaded PLGA nanoparticles by using emulsion solvent evaporation technique. Polyvinyl alcoh...

BACKGROUND A novel lovastatin (LVT)-loaded poly(lactic acid) microsphere suitable for oral administration was developed in this study, and in vitro and in vivo characteristics were evaluated. METHODS The designed microspheres were obtained by an improved emulsion-solvent evaporation method. The morphological examination, particle size, encapsulation ratio, drug loading, and in vitro release w...