Background: The biochemical characteristics of the follicular fluid (FF) play essential role in oocyte quality, the subsequent fertilization potential and embryo development. The oocyte quality and metabolism largely depends on follicular microenvironment. Present study aimed to investigate the relationship between oocyte quality and FF homocysteine (Hcy) level in women undergoing to IVF treatm...

Background: Recently, it has been found that exposure of sperm to PVP may cause submicroscopic changes in sperm structure and the sperm nucleus. The PVPinduced nuclear damage may have been due to breakdown of sperm membranes. Consequently, it is probable that exposure of sperm to PVP may impair embryo development. There are apparently no detailed reports regarding the specific effects of PVP on...

clinical reproductive centers produce large amounts of surplus poor-quality embryos annually, how to maximize the use of these embryos, and which of them have the potential to develop into blastocyst stage and influencing factors were lack of systematic research. objective: to investigate the fate of surplus poor-quality embryos which were cultured to obtain blastocyst, determine the factors wh...

BACKGROUND Women with hyper-and hypothyroidism are at increased risk for infertility and adverse pregnancy outcomes. Whether in women considered euthyroid thyroid function (TSH values) and thyroid autoimmunity (thyroid antibodies) influence in vitro fertilization (IVF) cycle outcome has, however, remained controversial. Any such effect should be easily visible in women with low functional ovari...

Background: Diabetes mellitus is a metabolic condition characterized by elevated blood glucose levels secondary to absolute impairment of insulin secretion. Maternal diabetes has been demonstrated to adversely affect pre implantation embryo development and pregnancy outcomes. Emerging evidence has implicated that these effects are associated with compromised oocyte competence. Several developme...

This prospective study was undertaken to reassess the prognostic value of leptin during critical stages of in vitro fertilization-embryo transfer (IVF-ET) and address its role in the functional staging of assisted reproductive technologies at the level of embryo quality. Serum and follicular fluid samples of 100 selected women undergoing the long IVF-ET protocol were collected for leptin and em...

Background: The aim of our study was to determine the metabolic profile: glucose, triglycerides (TG), high density lipoprotein (HDL) and cholesterol (CHT) in women undergoing ART (Assisted reproductive technology) cycles and estimate its effect on In Vitro Fertilization (IVF) outcomes Materials and Methods: Forty three women undergoing IVF treatment were included in the study. Patients were all...

background: determination of oocyte fertilization and embryo quality are one of the most important purposes in art cycles. follicular fluid provides an important microenvironment for development of oocytes and some biochemical characteristics of the follicular fluid, such as pregnancy-associated plasma protein-a (papp-a), may play an important role in prediction of success rate of art. objectiv...