نتایج جستجو برای: embryo arrest

تعداد نتایج: 123218  

Journal: :international journal of fertility and sterility 0
maria maurer thomas ebner manuela puchner richard bernhard mayer omar shebl peter oppelt

background: selecting the best embryo for transfer, with the highest chance of achieving a vital pregnancy, is a major goal in current in vitro fertilization (ivf) technology. the high rate of embryonic developmental arrest during ivf treatment is one of the limitations in achieving this goal. chromosomal abnormalities are possibly linked with chromosomal arrest and selection against abnormal f...

Journal: :Reproduction 2005
Bart Mateusen Ann Van Soom Dominiek G D Maes Isabelle Donnay Luc Duchateau Anne-Sophie Lequarre

Porcine embryo selection prior to transfer is mainly influenced by morphological criteria. However, the relationship between embryonic morphology, developmental potential and cell death by apoptosis in porcine embryos is still unclear. The aim of this study was to establish embryo quality parameters for in vivo fertilised porcine embryos based on timing of development in vitro, embryo morpholog...

Bayat PD Darabi MR, Nedjadi AD

Background: Decreasing the growth and developmental rate of embryo and arresting in certain step of development like two cell block could be the reason of infertility in some couples referring to fertility and infertility center. The aim of this study is the effect of strontium on growth and development of two-cell arrested NMRI mouse embryo. Materials and Methods: The female mice were coupled ...

2010
Vinita A. Hajeri Brent A. Little Mary L. Ladage Pamela A. Padilla

Oxygen, an essential nutrient, is sensed by a multiple of cellular pathways that facilitate the responses to and survival of oxygen deprivation. The Caenorhabditis elegans embryo exposed to severe oxygen deprivation (anoxia) enters a state of suspended animation in which cell cycle progression reversibly arrests at specific stages. The mechanisms regulating interphase, prophase, or metaphase ar...

2014
Dean H. Betts Nathan T. Bain Pavneesh Madan

The in vitro production of mammalian embryos suffers from high frequencies of developmental failure due to excessive levels of permanent embryo arrest and apoptosis caused by oxidative stress. The p66Shc stress adaptor protein controls oxidative stress response of somatic cells by regulating intracellular ROS levels through multiple pathways, including mitochondrial ROS generation and the repre...

Journal: :The Journal of Cell Biology 2003
Olivier D. Lohez Caroline Reynaud Franck Borel Paul R. Andreassen Robert L. Margolis

p53 and the retinoblastoma (RB) pocket proteins are central to the control of progression through the G1 phase of the cell cycle. The RB pocket protein family is downstream of p53 and controls S-phase entry. Disruption of actin assembly arrests nontransformed mammalian fibroblasts in G1. We show that this arrest requires intact RB pocket protein function, but surprisingly does not require p53. ...

Journal: :PLoS ONE 2008
Sunny H. Jun Bokyung Choi Lora Shahine Lynn M. Westphal Barry Behr Renee A. Reijo Pera Wing H. Wong Mylene W. M. Yao

BACKGROUND Hundreds of thousands of human embryos are cultured yearly at in vitro fertilization (IVF) centers worldwide, yet the vast majority fail to develop in culture or following transfer to the uterus. However, human embryo phenotypes have not been formally defined, and current criteria for embryo transfer largely focus on characteristics of individual embryos. We hypothesized that embryo ...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2014
Mohammad M Rahman Simona Rosu Daphna Joseph-Strauss Orna Cohen-Fix

The cell cycle is a highly regulated process that enables the accurate transmission of chromosomes to daughter cells. Here we uncover a previously unknown link between the tricarboxylic acid (TCA) cycle and cell cycle progression in the Caenorhabditis elegans early embryo. We found that down-regulation of TCA cycle components, including citrate synthase, malate dehydrogenase, and aconitase, res...

Journal: :Human reproduction 2000
I De Croo J Van der Elst K Everaert P De Sutter M Dhont

The aetiology of azoospermia can be grossly divided into obstructive and non-obstructive causes. Although in both cases testicular spermatozoa can be used to treat male fertility, it is not well established whether success rates following intracytoplasmic sperm injection (ICSI) are comparable. Therefore, a retrospective analysis of fertilization, pregnancy and embryo implantation rates was perf...

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