Introduction According to the wavefront-phenomenon myocardial infarction scar should have a larger extent on the subendocardial than the subepicardial surface. This is important for differentiating ischemic from nonischemic lesions in late gadolinium enhancement (LGE) images. In hypertrophic obstructive cardiomyopathy septal ablation (TASH) with injection of microparticles instead of ethanol re...

An arteriovenous malformation model with a transparent nidus was constructed to investigate the embolization behavior of polyvinyl acetate (PVAc) solution relative to flow velocity in the feeding artery and injection speed. It was found that the liquid embolic material flowed distally when injected too fast or when the flow velocity was too low. In addition, we found that solution consisting of...

Zinc is prevalent in the mammalian central nervous system and its role in ischemic brain injury is still controversial. In the present study, the effect of zinc in ischemic brain injury was examined in an embolic model of stroke in rats. Furthermore, the effect of zinc in combination with bicuculline, a GABAa antagonist, was also examined in the ischemic injury. Treatment with zinc or zinc plus...

The wavelet analysis of the Doppler heart sound detected under controlled venous air embolism at sub-clinically and clinically significant volumes was studied in anaesthetized dogs. Signal processing with wavelet enhances the power of embolic signal and facilitates the simple detection and extraction of embolic heart beats by thresholding. The cumulative power of the extracted embolic heart bea...

BACKGROUND AND PURPOSE Liquid embolic agents are increasingly used to treat vascular malformations. We sought to assess embolization with these agents by using a dual-lumen balloon catheter in an experimental setting. MATERIALS AND METHODS Eighteen injections of liquid embolic agents were performed in the rete mirabile of swine. We used 3 methods to control liquid embolic agent reflux: 1) dua...

objective(s): stroke poses a crucial risk for mortality and morbidity. our study aimed to investigate the effect of p-coumaric acid on focal cerebral ischemia in rats. material and methods: rats were randomly divided into four groups, namely group i (control rats), group ii (ischemia rats), group iii (6 hr ischemia + p-coumaric acid rats) and group iv (24 hr ischemia + p-coumaric acid rats). ce...

BACKGROUND AND PURPOSE The main issue with use of a liquid embolic agent is one of safety. To determine and improve the efficacy of potential neuroendovascular treatment regimens, particularly the use of liquid embolic agents, we evaluated the changes in aneurysm flow dynamics resulting from alterations of parent vessel flow. METHODS We created silicone replicas of a laboratory-created aneury...