the invention of the drug-eluting stent (des) has brought about revolutionary changes in the field of interventional cardiology. in the des era, in-stent restenosis has declined but new issues such as stent thrombosis have emerged. one of the emerging paradigms in the des era is stent fracture. there are reports about stent fracture leading to in-stent restenosis or stent thrombosis. most of th...

BACKGROUND Previous research suggests that the early benefit from revascularization with drug-eluting stents might diminish over time. METHODS We performed an extended analysis of a previously identified cohort of 6440 patients who underwent percutaneous coronary intervention between April 1, 2003 and March 31, 2005 using a prospective provincial clinical registry in Alberta, Canada. We compa...

BACKGROUND Numerous studies have compared the outcomes of coronary artery bypass grafting (CABG) surgery and coronary stenting for the treatment of multivessel coronary disease. In 2003, drug-eluting stents were introduced with the hope of reducing restenosis. However, limited information exists on the comparison of drug-eluting stents and CABG surgery. The long-term outcome of drug-eluting ste...

BACKGROUND Drug-eluting stents have been seen as an attractive alternative to bare-metal stents for percutaneous coronary interventions (PCIs) because of the decreased need for revascularization. However, comparative clinical trials have shown no difference in patient outcomes, and drug-eluting stents are considerably more expensive than their bare-metal counterparts. We conducted a systematic ...

background: small side branches, albeit less important than their larger counterparts, have not yet received due attention in the literature. nor has there ever been a comparison between drug-eluting stents and bare metal stents apropos side branch occlusion . the aim of this study was to compare the patency of small (≥0.5 and ≤1.5 mm in diameter) side branches with respect to bare metal vs. dr...

the coarctation of the aorta (coa) is rare in adulthood. diagnosis is made by clinical suspicion and physical findings such as blood pressure difference between the upper and lower extremities, pulse delay in the femoral artery, and systolic murmur over the thoracic spine.the coa in adulthood and in patients with associated aneurysm is challenging and different complications even with proper tr...

OBJECTIVE To compare the efficacy and safety of biodegradable polymer drug eluting stents with those of bare metal stents and durable polymer drug eluting stents. DESIGN Mixed treatment comparison meta-analysis of 258,544 patient years of follow-up from randomized trials. DATA SOURCES AND STUDY SELECTION PubMed, Embase, and Central were searched for randomized trials comparing any of the Fo...

OBJECTIVE To evaluate the intermediate-term outcomes of patients with unprotected left main coronary artery stenosis who were treated with percutaneous coronary intervention in Hong Kong. DESIGN Historical cohort. SETTING A regional hospital in Hong Kong. PATIENTS Patients with unprotected left main coronary artery disease undergoing stenting with bare-metal stents or drug-eluting stents ...

AIMS To provide systematic assessment of the clinical effectiveness of drug-eluting stents (DES) versus non-DES to inform national guidance. METHODS AND RESULTS The review was conducted according to internationally recognised methods. The search strategy identified published (7) and unpublished (7) randomised controlled trials comparing the use of DES to non-DES. Outcomes included death, acut...

The prospective multicenter German Drug-Eluting Stent (DES.DE) registry is an observational study to analyze and evaluate the therapeutic principle of the differential drug-eluting stents (sirolimus- and paclitaxel-eluting stents) and bare metal stents under real world conditions in the context of the German healthcare system. The baseline clinical and angiographic characteristics and follow-up...