IN THE CONTEXT of history scientists often share the fate of artists, for the final judgment of their work is subject to the whims of later generations. Even a great scientist may fade into obscurity as later investigators incorporate his ideas into their own and forget their origin. Such a fate seems to have befallen John Scott Burdon-Sanderson. Working in the last two decades of the nineteent...

Noninvasive imaging of cardiac electrophysiology is still a major goal despite all recent technical innovations. This review gives an overview about the historical background, recent developments and possible future applications of noninvasive imaging of cardiac electrophysiology.

This work proposes an optimal control approach for the termination of re-entry waves in cardiac electrophysiology. The control enters as an extracellular current density into the bidomain equations which are well established model equations in the literature to describe the electrical behavior of the cardiac tissue. The optimal control formulation is inspired, in part, by the dynamical systems ...

• Although voltage clamp methods have been applied experimentally to cardiac tissue for over a decade, this field of study has failed to achieve general acceptance because of limitations of the experimental approach and difficulty in interpreting the results. Yet this technique is valuable within its limitations, and to dismiss it would be to lose a valuable tool. In perspective, most technique...

The advent of electrophysiology (EP) testing revolutionized the care of children with arrhythmia. Precise mechanistic and anatomical diagnosis of arrhythmias became possible. The later development of catheter-based ablation transformed the care of these children by allowing many arrhythmias to be cured during the same procedure. Indications for EP testing vary depending on the age of the child,...