Discrete fluctuations in conductance of lipid bilayer membranes may be observed during the initial stages of membrane interaction with EIM ("excitability inducing material"), during destruction of the EIM conductance by proteolysis, and during the potential-dependent transitions between low and high conductance states in the "excitable" membranes. The discrete conductance steps observed during ...

OBJECTIVES There is a need for better, noninvasive quantitative biomarkers for assessing the rate of progression and possible response to therapy in spinal muscular atrophy (SMA). In this study, we compared three electrophysiological measures: compound muscle action potential (CMAP) amplitude, motor unit number estimate (MUNE), and electrical impedance myography (EIM) 50 kHz phase values in a m...

Abstract This article re-examines the nonlinear vibration and bending responses of porous sandwich cylindrical panels reinforced by graphene platelets resting on elastic foundations in thermal environments. The platelet-reinforced composite (GPLRC) core is assumed to be multilayers, each layer may have different porosity coefficient values achieve a piece-wise functionally graded pattern. By in...

Electrical impedance myography (EIM) provides a non-invasive approach for quantifying the severity of neuromuscular disease. Here we determine how well EIM data correlates to functional and ultrasound (US) measures of disease in children with Duchenne muscular dystrophy (DMD) and healthy subjects. Thirteen healthy boys, aged 2-12 years and 14 boys with DMD aged 4-12 years underwent both EIM and...

Synoptic eddy–mean flow interaction has been recognized as one of the key sources for extratropical lowfrequency variability. In this paper, the underlying dynamics of this interaction are examined from the perspective of a synoptic eddy-induced dynamic instability. To delineate this instability, a barotropic model is used that is linearized with respect to a stochastic basic flow prescribed wi...

Extraintestinal manifestations (EIM) in inflammatory bowel disease (IBD) are frequent and may occur before or after IBD diagnosis. EIM may impact the quality of life for patients with IBD significantly requiring specific treatment depending on the affected organ(s). They most frequently affect joints, skin, or eyes, but can also less frequently involve other organs such as liver, lungs, or panc...

Evolution-in-materio (EIM) is a method that uses artificial evolution to exploit the properties of physical matter to solve computational problems without requiring a detailed understanding of such properties. EIM has so far been applied to very few computational problems. We show that using a purpose-built hardware platform called Mecobo, it is possible to evolve voltages and signals applied t...

Although interaction effects can be exploited to improve predictions and allow for valuable insights into covariate interplay, they are given limited attention in analysis. Interaction forests a variant of random categorical, continuous, survival outcomes that explicitly models quantitative qualitative bivariable splits performed by the trees constituting forests. The new effect importance meas...

preprint numerics no. 3/2011 norwegian university of science and technology trondheim, norway In this paper, we introduce two parameter multi-domain " hp " techniques for the empirical interpolation method (EIM). In both approaches, we construct a partition of the original parameter domain into parameter subdomains: h-refinement. We apply the standard EIM independently within each subdomain to ...