epidermal nevus syndrome is a rare congenital disorder, characterized by epidermal nevi and multiple organ involvement. multicystic kidney disease has been very rarely reported in this syndrome. here is the report of a boy presented with multiple epidermal nevi, cardiac anomaly, seizure attack, hemi hypertrophy, and multicystic dysplastic kidney complicated with wilms' tumor. according to this ...

The article by Shapiro et al., which summarizes a survey of respondents on the words or phrases they use to identify the melanocytic nevus described by Clark et al. in 1978, shows that over 70% of The American Society of Dermatopathology (ASDP) members and nearly 85% of The American Academy of Dermatology (AAD) members preferred one of the following phrases: ‘‘dysplastic nevus’’, ‘‘nevus with a...

BACKGROUND Nevi with cytologic characteristics of Spitz nevus and architectural features of Clark's/dysplastic nevus are not well recognized in the literature. METHODS Twenty-seven nevi with characteristics of Spitz nevus and Clark's/dysplastic nevus are reviewed. RESULTS The patients' mean age was 33 years, and 17/27(63%) patients were female. Lesions were most frequent on the trunk and lo...

Actas Dermosifiliogr. 2009;100:615-34 626 some forms of brain tumor; although such outcomes have not been demonstrated for melanoma. The cells of retinoblastoma, melanoma and dysplastic nevus are derived from the neural crest. There are authors who postulate that patients with retinoblastoma and dysplastic nevus syndrome have increased genetic susceptibility to melanoma due to a primary anomaly...

The aim of the present study was to evaluate the frequency with which histologically confirmed dysplastic nevi are observed among patients with superficial spreading melanoma compared to patients with nodular melanoma. A pathology review of 117 new cases of first primary nonfamilial cutaneous melanoma identified 61 patients with superficial spreading melanoma and 19 with nodular melanoma. Study...

BACKGROUND Three cases of pointillist nevus, which is a distinctive clinical type of benign melanocytic nevus with variegated pigment, have been described in the literature to date. OBSERVATIONS A 24-year-old man presented with an acquired melanocytic lesion composed of multiple tiny pigmented dots. Dermoscopy revealed multiple brown globules on a reddish skin-colored background, and histolog...

Nevus depigmentosus is a stable and well-circumscribed congenital hypomelanosis that may be in an isolated, dermatomal or systemic form. An 18-yr-old Korean man with segmental nevus depigmentosus developed multiple pigmented nevi which were present only within the confines of the leukoderma. Histologic and electron microscopic studies rendered a diagnosis of nevus depigmentosus with dysplastic ...