The aim of this study was to evaluate the role of lysosomal enzymes in excessively heavy menstruation by comparing women with menorrhagia due to dysfunctional bleeding or intrauterine contraceptive device (IUCD) use with those with normal menstrual periods or with amenorrhoea associated with breastfeeding. This was a prospective cohort investigation of the activity of four endometrial lysosomal...

Abnormal uterine bleeding is one of the most common reasons for women to seek for care. Dysfunctional uterine bleeding describes the spectrum of abnormal bleeding patterns in the abscence of a medical illness or pelvic pathology. It is responsible for about half of the women with abnormal uterine bleeding in reproductive age (Ewenstein, 1996). It mainly presents as menorrhagia, hence, the term ...

Dysfunctional Uterine Bleeding (DUB) is one of the most common and significant gynaecological complaints seen in about 10-15% of women attending a gynaecological clinic. DUB is excessive abnormal bleeding from the endometrium that is unrelated to any anatomic lesions of the genital tract. The largest incidence of DUB is in the women of the childbearing age group and menorrhagia was more common ...

Background: The term dysfunctional uterine bleeding(DUB) refers to any abnormal bleeding from the uterus, unassociated with tumour, inflammation and pregnancy. The histological diagnosis of DUB is very essential for adequate management especially in perimenopausal and postmenopausal females. The present study was undertaken with the aim of evaluating DUB in various age groups, carry out histopa...

Abnormal Uterine Bleeding (AUB) is a common cause for concern among adolescents and their families, as well as a frequent cause of visits to the Emergency Department and/or health care provider. (1) While there are many etiologies of AUB, the one most likely among otherwise healthy adolescents is Dysfunctional Uterine Bleeding (DUB).

In 2011, the FIGO classification system (PALM-COEIN) was published to standardize terminology, diagnostic and investigations of causes of abnormal uterine bleeding (AUB). According to FIGO new classification, in the absence of structural etiology, the formerly called "dysfunctional uterine bleeding" should be avoided and clinicians should state if AUB are caused by coagulation disorders (AUB-C)...

Abnormal uterine bleeding is one of the commonest disorder in the female, which needs thorough investigation to ascertain the exact aetiological basis so that a proper treatment can be rendered to such cases. Rumbolz and Greene (1957) studied mast cells in the endometrium in different physiological and pathological conditions and observed definite increase of mast cells in the secretory phase, ...