OBJECTIVE To determine the diagnostic accuracy of Diffusion-Weighted Magnetic Resonance Imaging (DWMRI) in the detection of myometrial invasion in endometrial cancer taking histopathology as gold standard. STUDY DESIGN Cross-sectional validation study. PLACE AND DURATION OF STUDY Department of Radiology, The Aga Khan University Hospital, Karachi, from January to December 2012. METHODOLOGY...

Objective: The purpose of our study was to evaluate the utility of the apparent diffusion coefficient (ADC) value measurement in the diagnosis of peritoneal metastases on diffusion weighted magnetic resonance imaging. Materials and Methods: Diffusion weighted imaging with conventional magnetic resonance imaging sequences was performed on twenty consecutive oncology patients (group I) with perit...

Electroporation, is known to induce cell membrane permeabilization in the reversible (RE) mode and cell death in the irreversible (IRE) mode. Using an experimental system designed to produce a continuum of IRE followed by RE around a single electrode we used MRI to study the effects of electroporation on the brain. Fifty-four rats were injected with Gd-DOTA and treated with a G25 electrode impl...

PURPOSE To exploit the intravoxel incoherent motion (IVIM) diffusion-weighted (DW) MRI when evaluating the therapeutic response of gastrointestinal stromal tumors (GIST) to Imatinib in a mouse model. MATERIALS AND METHODS Mice with xenografts bearing cells from the GIST-T1 cell line were randomly divided into a treated group receiving Imatinib and a control group. DWMRI scans with 14 b-values...

Abstract Various materials and compounds have been used in the design of diffusion-weighted magnetic resonance imaging (DWMRI) phantoms to mimic biological tissue properties, including diffusion. This review thus provides an overview preparations various DW-MRI available relation limitations strengths materials/solutions fill them. The narrative conducted from relevant databases shows that synt...

Introduction We present a natural framework for group-wise comparison of the regional variation of tissue parameters estimated from diffusion-weighted MRI (DW-MRI) over an anatomical region of interest (ROI). The regional variation model (RVM) fits curves of parameter variation directly to the DWMRI signals which captures the spatial changes in a natural way as well as reducing the effects of n...

In this paper, we compare a representative selection of current state-of-the-art algorithms in diffusion-weighted magnetic resonance imaging (dwMRI) tractography, and propose a novel way to quantitatively define the connectivity between brain regions. As criterion for the comparison, we quantify the connectivity computed with the different methods. We provide initial results using diffusion ten...