Case-Based Reasoning research has reached a state where a large number of basic problems seems to be “solved”. However, techniques originally developed for CBR applications are being applied in systems that are not CBR systems in the original meaning of the word. This paper wants to extend the traditional view of CBR to overcome its former limitations, to open new fields of research, and to ope...

Detection and accurate quantification of treatment delivery errors is important in radiation therapy. This study aims to evaluate the accuracy of DVH based QA in quantifying delivery errors. Eighteen previously treated VMAT plans (prostate, H&N, and brain) were randomly chosen for this study. Conventional IMRT delivery QA was done with the ArcCHECK diode detector for error-free plans and plans ...

We evaluated dose-volume histogram (DVH) parameters based on deformable image registration (DIR) between brachytherapy (BT) and external beam radiotherapy (EBRT) that included a center-shielded (CS) plan. Eleven cervical cancer patients were treated with BT, and their pelvic and CS EBRT were studied. Planning CT images for EBRT and BT (except for the first BT, used as the reference image) were ...

Purpose To develop statistical dose-volume histogram (DVH)-based metrics and a visualization method to quantify the comparison of treatment plans with historical experience and among different institutions. Methods and materials The descriptive statistical summary (ie, median, first and third quartiles, and 95% confidence intervals) of volume-normalized DVH curve sets of past experiences was ...

PURPOSE Adaptive radiation therapy (ART) can reduce normal tissue toxicity and/or improve tumor control through treatment adaptations based on the current patient anatomy. Developing an efficient re-planning algorithm is an important step for ART. For the re-planning process, manual trial-and-error approach to fine-tune planning parameters is a time- consuming and resource-requiring task. Howev...

Radiation therapy is an important modality in treating various cancers. Various treatment planning and delivery technologies have emerged to support Intensity Modulated Radiation Therapy (IMRT), creating significant opportunities to advance this type of treatment. We investigate the possibility of including the dose prescription, specified by the Dose Volume Histogram (DVH), within the convex o...

Radiation therapy is an important modality in treating various cancers. Various treatment planning and delivery technologies have emerged to support Intensity Modulated Radiation Therapy (IMRT), creating significant opportunities to advance this type of treatment. We investigate the possibility of including the dose prescription, specified by the Dose Volume Histogram (DVH), within the convex o...

The first quality assurance process for validating dose-volume histogram data involving brachytherapy procedures in radiation therapy is presented. The process is demonstrated using both low dose-rate and high dose-rate radionuclide sources. A rectangular cuboid was contoured in five commercially available brachytherapy treatment planning systems. A single radioactive source commissioned for QA...

PURPOSE: In radiation therapy treatment planning systems, structures are represented as parallel 2D contours. For treatment planning algorithms, structures must be converted into labelmap (i.e. 3D image denoting structure inside/outside) representations. This is often done by triangulated a surface from contours, which is converted into a binary labelmap. This surface to binary labelmap convers...

Radiation therapy is an important modality in treating various cancers. Various treatment planning and delivery technologies have emerged to support intensity modulated radiation therapy (IMRT), creating significant opportunities to advance this type of treatment. However, one of the fundamental questions in treatment planning and optimization, 'can we produce better treatment plans relying on ...