نتایج جستجو برای: durable resistance

تعداد نتایج: 387540  

2015
Shuichi Fukuoka Norikuni Saka Yuko Mizukami Hironori Koga Utako Yamanouchi Yosuke Yoshioka Nagao Hayashi Kaworu Ebana Ritsuko Mizobuchi Masahiro Yano

Effective control of blast, a devastating fungal disease of rice, would increase and stabilize worldwide food production. Resistance mediated by quantitative trait loci (QTLs), which usually have smaller individual effects than R-genes but confer broad-spectrum or non-race-specific resistance, is a promising alternative to less durable race-specific resistance for crop improvement, yet evidence...

Journal: :Cancer discovery 2018
Yelena Y Janjigian Francisco Sanchez-Vega Philip Jonsson Walid K Chatila Jaclyn F Hechtman Geoffrey Y Ku Jamie C Riches Yaelle Tuvy Ritika Kundra Nancy Bouvier Efsevia Vakiani Jianjiong Gao Zachary J Heins Benjamin E Gross David P Kelsen Liying Zhang Vivian E Strong Mark Schattner Hans Gerdes Daniel G Coit Manjit Bains Zsofia K Stadler Valerie W Rusch David R Jones Daniela Molena Jinru Shia Mark E Robson Marinela Capanu Sumit Middha Ahmet Zehir David M Hyman Maurizio Scaltriti Marc Ladanyi Neal Rosen David H Ilson Michael F Berger Laura Tang Barry S Taylor David B Solit Nikolaus Schultz

The incidence of esophagogastric cancer is rapidly rising, but only a minority of patients derive durable benefit from current therapies. Chemotherapy as well as anti-HER2 and PD-1 antibodies are standard treatments. To identify predictive biomarkers of drug sensitivity and mechanisms of resistance, we implemented prospective tumor sequencing of patients with metastatic esophagogastric cancer. ...

2015
Lu Hou Xianming Chen Meinan Wang Deven R. See Shiaoman Chao Peter Bulli Jinxue Jing

Winter wheat Druchamp has both high-temperature adult-plant (HTAP) resistance and all-stage resistance to stripe rust caused by Puccinia striiformis f. sp. tritici (Pst). The HTAP resistance in Druchamp is durable as the variety has been resistant in adult-plant stage since it was introduced from France to the United States in late 1940s. To map the quantitative trait loci (QTL) for stripe rust...

Journal: :The New phytologist 2015
Romain Bourget Loïc Chaumont Charles-Eric Durel Natalia Sapoukhina

Quantitative plant disease resistance is believed to be more durable than qualitative resistance, since it exerts less selective pressure on the pathogens. However, the process of progressive pathogen adaptation to quantitative resistance is poorly understood, which makes it difficult to predict its durability or to derive principles for its sustainable deployment. Here, we study the dynamics o...

2006
R. Scorza M. Ravelonandro

Genetic resistance to Plum pox virus (PPV) is the most viable alternative for long-term control of sharka disease. In addition to the classical approaches to producing resistant germplasm and cultivars, genetic transformation offers a promising genetic approach to resistance. We show, using the example of C5 plum, that genetically engineered resistance can provide durable, stable and high level...

Protective coatings that resist oxide scale growth and decrease chromium evaporation are necessary to makestainless steel interconnect materials for long-term durable operation of solid oxide fuel cells (SOFCs). Inthis study a layer of manganese was coated on the surface of AISI 441 ferritic stainless steel which is used insolid oxide fuel cells for interconnect applications. The oxidation beha...

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