Currents were elicited by acetylcholine (ACh), by d-tubocurarine (dTC), and by mixtures of ACh and dTC, from stably transformed fibroblasts that express fetal or adult muscle nicotinic receptors. dTC acted as an antagonist of ACh for activation of adult-type receptors, whereas it acted as a weak partial agonist at fetal-type receptors. The channel-blocking action of dTC was not apparent at the ...

DTC is strategy of selecting proper stator voltage vectors to reduce torque error and flux error. DTC uses hysteresis band controller whose control action has no difference between large torque error and small one. This results in high torque ripple. In order to reduce the torque ripple and to improve the performance of DTC, DTC based on Fuzzy Logic is proposed in this paper. The simulations ar...

PURPOSE Clinical significance of disseminated tumor cells (DTC) in bone marrow of early breast cancer patients has been reported, but improvements in detection methods are needed. EXPERIMENTAL DESIGN Bone marrow aspirates from 621 patients with stage I to III breast cancer were screened for cytokeratin-positive (CK+) cells. CK+ cells were categorized into DTC only if they had specific morphol...

Purpose – The purpose of this study is to provide an overview of the economic and clinical impacts of direct-to-consumer (DTC) advertising on consumers and physicians. Design/methodology/approach – Controversy around the benefits and concerns associated with DTC advertising are summarized. The sources are sorted based on their position toward DTC promotions: defending or opposing. Two recent wo...

The mesenchymal distal tip cell (DTC) provides the niche for Caenorhabditis elegans germline stem cells (GSCs). The DTC has a complex cellular architecture: its cell body caps the distal gonadal end and contacts germ cells extensively, but it also includes multiple cellular processes that extend along the germline tube and intercalate between germ cells. Here we use the lag-2 DTC promoter to dr...

Differentiated thyroid cancer (DTC) is the second most common cancer in pregnancy. Its management is a challenge for both doctors and patients, and the best timing for surgery is unclear. A systematic review evaluating the prognosis of DTC in pregnant patients was conducted. After reviewing 401 unique citations and 54 full texts, 4 studies that compared the prognosis of patients with DTC relate...

OBJECTIVE The impact of childhood differentiated thyroid carcinoma (DTC) on psychosocial development has not yet been studied. The aim of this study was to evaluate the achievement of psychosocial developmental milestones in long-term survivors of childhood DTC. DESIGN AND METHODS Survivors of childhood DTC diagnosed between 1970 and 2013 were included. Reasons for exclusion were age <18 or >...

– Direct Torque Control using Multilevel Inverter (DTC-MLI) strategy has attracted a great deal of interest in recent years, in the field of high power induction machines or permanent magnet machines drives applications for high dynamic response. This proposal combines the advantages of the multilevel inverter with direct torque controlled based schemes. Numerous efforts have been accomplished ...

PURPOSE/OBJECTIVES To review the phenomenon of direct-to-consumer (DTC) advertising of prescription medications in the media, with an overview of pertinent studies in the literature regarding patients' and healthcare professionals' perspectives on DTC advertising. DATA SOURCES Journal articles, media, and clinical experience. DATA SYNTHESIS DTC advertising of prescription medications is ext...

Advanced differentiated thyroid cancer (DTC), defined by clinical characteristics including gross extrathyroidal invasion, distant metastases, radioiodine (RAI) resistance, and avidity for 18-fluorodeoxyglucose (positron emission tomography-positive), is found in approximately 10-20% of patients with DTC. Standard therapy (surgery, RAI, TSH suppression with levothyroxine) is ineffective for man...