the effectiveness of any drug supply systems in providing a trustworthy supply of essential drugs is a critical issue. to evaluate this effectiveness, it is necessary to watch over the status of the essential medicines in any country impartially and continuously. some countries and also the world health organization (who) have codified a list of minimum medicines needed for a basic health care ...

BACKGROUND Previous studies have described drug shortages; however, there has been no comprehensive evaluation focusing on US antibacterial shortages. METHODS Drug shortage data from the University of Utah Drug Information Service database were analyzed, with a focus on antibacterial agents from 2001 to 2013. We used descriptive statistics to describe trends in drug shortages, analyze drug cl...

Drug shortages have increasingly been a problem for pharmacists and clinicians over the past decade. Clinicians need to be aware of the various causes of drug shortages and the issues that may arise as a result, particularly as they relate to medication safety. Numerous resources and strategies are available to mitigate the effects of drug shortages, and clinicians should work with their health...

Acute and chronic shortages of various pharmaceuticals and particularly of sterile injectable products are being reported on a global scale, prompting evaluation of more effective strategies to manage current shortages and development of new, high-quality pharmaceutical products to mitigate the risk of potential future shortages. Oncology drugs such as liposomal doxorubicin and 5-fluorouracil r...

J Adv Pract Oncol 2012;3:96–102 T he issue of drug shortages is only one of the many crucial concerns facing oncology advanced practitioners (APs) in the United States today. However, it may be the most critical issue affecting shortand long-term patient outcomes. Shortterm outcomes may be affected by treatment delays, treatment with less effective alternatives, and increased toxicity. Long-ter...

Second-line drugs (SLDs) are essential for treating multidrug-resistant and extensively drug-resistant tuberculosis (MDR TB* and XDR TB†). Drug shortages, in which supplies of all clinically interchangeable versions of a given Food and Drug Administration (FDA)-regulated drug become inadequate to meet actual or projected user demand, have been well-documented in many areas of medicine; for seve...

Drug shortages are a complex and global phenomenon. When a drug cannot be delivered at the moment of patient demand, every stakeholder in the health care system is affected. The aim of this study was to investigate the characteristics, clinical impact, financial impact and management of drug shortages in European hospital pharmacies and identify opportunities for prevention and mitigation of dr...

Financial plans of clinical commissioning groups are being derailed by emergency hikes in prices of generic drugs, which have led to soaring costs, The BMJ has learnt. Last month The BMJ reported that ongoing shortages of generic drugs cost the NHS £38m in November 2017, as the government agreed more emergency price increases to boost stocks. An examination of board papers by The BMJ has found ...

Pharmaceutical drug shortages are multifaceted and complex problems that affect all aspects of health care, including patients, caregivers, healthcare providers, third-party payers, the pharmaceutical industry, and regulators. Drug shortages have increased significantly since 2000, which cause increases in healthcare costs and compromised patient care. New government regulations have led the U....