conclusions the results of the antibiotic resistance and other data suggest that there is a possible common clone of e. faecalis, which could rapidly disseminate in patients and the environment. results the results indicated that, 86% of patient and 29% of environmental isolates carried ebp genes. the ability of the isolates to strongly attach was 62% and 71% for patient and environmental sampl...

conclusions our findings revealed that the zfn technology could be employed to overcome ampicillin resistance by the targeted disruption of the ampicillin resistance gene, which leads to inactivation of β-lactam synthesis. therefore, zfn technology could be engaged to decrease the antibiotic resistance issue with the construction of a zfn archive against different args. to tackle the resistance...

conclusions carrier samples screening is considered inferior to clinical samples. treatment of a variety of infectious diseases is difficult due to resistant bacteria. consequently, annual screening of these individuals, detecting the carriers and decolonizing them to reduce transmission of s. aureus in the hospital are necessary. background methicillin-resistant staphylococcus aureus (mrsa) is...

introduction: drug resistant staphylococci are the most important agents of nosocomial infections. in this survey, effect of different antibiotics on these bacteria and their drug resistance was investigated. methods: the study included 500 strains of staphylococci. minimum inhibitory concentrations of all antibiotics was determined by the broth macro dilution technique and standard methods fro...

conclusions the results suggest that fge can improve the antibiotic sensitivity of these pathogens to some antibiotics. results fresh garlic extract displayed evident inhibition properties against c. albicans and mrsa, yet weak inhibition properties against p. aeruginosa. additionally, fge showed the potential to improve the effect of antibiotics on antibiotic resistant pathogens. the synergism...

introduction: ventilator-associated pneumonia (vap) is one of the most common hospital infections and a side effect of lengthy stay in intensive care unit (icu). considering the ever-changing pattern of common pathogens in infectious diseases and the raise in prevalence of hospital infections, the present study was designed aiming to determine the prevalence of vap and its bacterial causes. met...

We show that Escherichia coli isolates originating from Arctic birds carry antimicrobial drug resistance determinants. This finding implies that dissemination of drug-resistant bacteria is worldwide. Resistance genes can be found even in a region where no selection pressure for resistance development exists.

Globally, pneumonia is considered to be the biggest killer of infants and young children (aged <5 years) outside the neonatal period, with the greatest disease burden in low- and middle-income countries. Optimal management of childhood pneumonia is challenging in settings where clinicians have limited information regarding the local pathogen and drug resistance profiles. This frequently results...

background cystic fibrosis (cf) is a genetic disease with an autosomal recessive pattern of inheritance. cf caused by a mutation in the cystic fibrosis transmembrane conductance regulator (cftr) gene and characterized by impaired transport of chloride ions across the cell membrane. staphylococcus aureus, pseudomonas aeruginosa, and burkholderia cepacia have been identified in the cultures of re...

The emergence and spread of antibiotic resistance is a crisis in health care today. Antibiotic resistance is often horizontally transferred to susceptible bacteria by means of multidrug resistance plasmids that may or may not persist in the absence of antibiotics. Because bacterial pathogens often grow as biofilms, there is a need to better understand the evolution of plasmid persistence in the...