Discovery of the medicine or drug is time consuming and labour intensive process. Natural products have vast chemical diversity and it has ability to act on various biological systems. Plants and its products are the important elements in the plant medicine system. Many of the plant extracts currently used in the treatment of cancer therapy and those agents were also isolated from plants. Here ...

Modern medicinal plant drug discovery has provided pharmacologically active compounds targeted against a multitude of conditions and diseases, such as infection, inflammation, and cancer. To date, natural products from medicinal plants remain a solid niche as a source from which cancer therapies can be derived. Among other properties, one favorable characteristic of an anticancer drug is its ab...

conclusions detection and surveillance of the significant sites of mutations in hbv is crucial for clinicians to decide on the choice of antiviral treatment and further management of hepatitis b carriers. objectives this study was carried out to detect mutations in p gene of hepatitis b virus isolated from malaysian hbv carriers. materials and methods a total of 58 sera samples were analyzed by...

Natural substances have long served as sources of therapeutic drugs. Many substances have been derived from traditional medicine, e.g. digitalis (from Foxglove), ergotamine (from contaminated rye), quinine (from Cinchona), etc. More recently, many antibiotic, antifungal and anticancer agents have been derived from bacteria, fungi, plant and animal sources. While newer techniques of combinatoria...

For centuries, Aloe Vera has been used by many different cultures. The ancient Greeks, the Romans, the Babylonians, Indians and the Chinese have all used Aloe Vera as a medicinal plant. One of the common experimental cancer models is sarcoma-180. When Aloe was administered to mice bearing S-180 tumors, the tumor growth was inhibited. Aloe vera is a dietary supplement and not a regulated drug. T...

This article contains data on in vitro antimycobacterial activity and cytotoxicity of hydroethanolic crude extracts from five selected medicinal plant species traditionally used to treat tuberculosis in Ghanaian ethnomedicine, see "Medicinal plants used to treat TB in Ghana" [1]. The interpretation and discussion of these data and further extensive insights into drug discovery against tuberculo...

background: antioxidant activities of plant extracts are being studied to increase the shelf life of fish products. some plants such as urtica dioica l. (nettle) can be a good source of antioxidants. the objective of this study was to evaluate the effects of hydroalcoholic and water extracts of nettle leaf on the chemical properties of superchilled minced meat of the common kilka fish (clupeone...

For centuries, Aloe Vera has been used by many different cultures. The ancient Greeks, the Romans, the Babylonians, Indians and the Chinese have all used Aloe Vera as a medicinal plant. One of the common experimental cancer models is sarcoma-180. When Aloe was administered to mice bearing S-180 tumors, the tumor growth was inhibited. Aloe vera is a dietary supplement and not a regulated drug. T...

BACKGROUND Tuberculosis (TB) is the second leading cause of death from a single infectious organism, demanding attention towards discovery of novel anti-tubercular compounds. Natural products or their derivatives have provided more than 50% of all existing drugs, offering a chemically diverse space for discovery of novel drugs. DESCRIPTION BioPhytMol has been designed to systematically curate...

HIV replication assays are important tools for HIV drug discovery efforts. Here, we present a full HIV replication system (EASY-HIT) for the identification and analysis of HIV inhibitors. This technology is based on adherently growing HIV-susceptible cells, with a stable fluorescent reporter gene activated by HIV Tat and Rev. A fluorescence-based assay was designed that measures HIV infection b...